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Genetic Ancestry Influences Dengue Severity Through Skin Immune Response
A novel study involving University of Pittsburgh and international collaborators shows that genetic ancestry alters immune responses in human skin explants infected with dengue virus. Findings...
AI Innovation Advances Breast Imaging Through Photoacoustic Computed Tomography
Caltech researchers have introduced a photoacoustic computed tomography (PACT) method for breast cancer imaging that combines sound’s deep tissue penetration with light’s molecular sensitivity....
Sage Therapeutics to Slash Workforce After Acquisition by Supernus Pharmaceuticals
Following its recent acquisition announcement, Sage Therapeutics plans to lay off nearly all employees, with state filings detailing a reduction of 338 jobs effective August 22. This move follows...
Novel Insights into Tauopathy: Neuronal Glycogen Breakdown Mitigates Neurodegeneration
Research from the Buck Institute reveals that glycogen accumulation in neurons exacerbates tauopathy diseases such as Alzheimer’s by impairing oxidative stress management. Restoration of glycogen...
Precise Robotic Hand Control Achieved via Noninvasive Brain-Computer Interface
Carnegie Mellon University researchers have demonstrated real-time, finger-level control of robotic hands using a noninvasive brain-computer interface (BCI). This milestone paves the way for...
Breakthrough in Low-Intensity Ultrasound Enables Targeted Cancer Therapy
Scientists at the Changchun Institute of Applied Chemistry have developed a targeted cancer treatment platform combining low-intensity ultrasound with therapeutic agents. This strategy enhances...
Whole-Genome Sequencing Boosts Diagnostic Yield in Sensorineural Hearing Loss
A collaborative study involving South Korean and US researchers utilized a comprehensive genetic testing workflow integrating whole-genome sequencing and functional analyses to diagnose over half...
AbbVie’s $2.1 Billion Bet on In Vivo CAR-T: Capstan Acquisition
AbbVie has agreed to acquire Capstan Therapeutics for up to $2.1 billion, expanding its pipeline into in vivo CAR-T therapies. Capstan, founded in 2022, develops CAR-T candidates targeting...
Immuno-Oncology Setbacks: Billions Lost on TIGIT Targeted Therapies
Pharma's once-promising TIGIT immuno-oncology target has collapsed after costly clinical failures, leading to billions lost. Key players including Bristol Myers Squibb, Gilead, GSK, and Novartis...
Ultrarare Disease Gene Therapies: Advances and Challenges
Recent advances in gene-editing technologies and regulatory approaches are enabling the development of therapies for ultrarare diseases affecting fewer than one in 50,000 people. A landmark case...
Alzheimer’s M&A Soars Post-Leqembi, Kisunla Approvals
Following FDA approvals of monoclonal antibodies Leqembi and Kisunla for Alzheimer’s disease, dealmaking in the space has surged dramatically. GlobalData reports Alzheimer’s M&A deal values jumped...
AI-Driven Drones and Precision Farming Innovations
Researchers at The Hebrew University of Jerusalem and partners have developed advanced drone systems integrating hyperspectral, thermal, and RGB sensors with AI algorithms to detect nitrogen and...
Breakthroughs in RNA Therapy Delivery and Efficacy
A University of Basel study published in Nature Communications reveals novel intracellular mechanisms restricting antisense oligonucleotide (ASO) therapies' effectiveness and identifies strategies...
Cancer Treatment Advances: New Targets and Radiotheranostics
Recent developments in oncology include Amgen’s FGFR2b-targeting antibody showing significant overall survival gains in a Phase 3 stomach cancer trial, albeit with ocular side effects raising...
Biotech Financing and Restructuring: Navigating Market Pressures
Applied DNA Sciences has restructured to focus on synthetic DNA manufacturing by closing its clinical lab and cutting 27% of staff, aiming to reduce costs and scale nucleic acid therapy...
AI and Biotech Integration: Accelerating Drug Discovery and Clinical Development
Innovative AI models developed by an OpenAI-backed startup have exhibited superior success in designing antibodies experimentally, outperforming existing protein modeling tools. Pfizer enhanced...
AbbVie’s $2.1 Billion Bet on In Vivo CAR-T - Capstan Deal
AbbVie has executed a major acquisition by purchasing Capstan Therapeutics for up to $2.1 billion, marking its entrance into the in vivo CAR-T therapy market. Capstan, founded in 2022, focuses on...
Moderna’s Flu Vaccine Wins Phase 3, FDA Submissions Expected
Moderna announced compelling phase 3 results for its mRNA-1010 influenza vaccine, demonstrating 26.6% improved efficacy over a licensed standard-dose comparator in adults 50 years and older. The...
Applied DNA Sciences Restructures to Prioritize Synthetic DNA Manufacturing
Applied DNA Sciences announced a strategic shift to focus exclusively on synthetic DNA manufacturing through its LineaRx subsidiary. The company ceased operations at its molecular and genetic...
Tempus AI Raises $400 Million to Reduce Debt Burden
Tempus AI announced plans to raise $400 million through convertible senior notes to pay down existing debt and reduce interest costs. The offering, maturing in 2030, includes an option for an...