Illumina partnered with the San Diego Zoo Wildlife Alliance to sequence up to 4,000 samples from the Frozen Zoo®, generating whole‑genome and multiomic data to inform conservation genetics, wildlife medicine, and biodiversity preservation. The collaboration will make sequence data available to the Zoo and collaborators and includes multiomic pilots to study viral integrations and evolutionary biology. The Frozen Zoo® is a five‑decade biobank with specimens from ~1,300 species; Illumina will apply WGS and multiomic assays to samples including high‑value collections like koalas. The project aims to translate genomic insights into conservation actions, breeding management and disease surveillance for threatened species. Large‑scale sequencing of biobanks creates reference genomes and population baselines that can guide captive breeding and reintroduction decisions; it also raises data sharing and ethical considerations for cross‑institutional conservation work. Watch for public datasets and applied case studies stemming from the program. Key actors: Illumina, San Diego Zoo Wildlife Alliance; reporting from company release and Nature Communications context.