Latest Biotech News

Sidewinder Therapeutics and Stipple Bio announced large financing rounds aimed at improving the targeting capabilities of antibody-drug conjugates. Both startups said they are on track to enter...

Seaport Therapeutics’ peer Hemab is joined by Avalyn Pharma as the IPO market shows renewed activity, with Avalyn filing a registration statement to raise capital for respiratory treatments. The...

A mouse-model study published in Cell Death Discovery reports that long-term administration of the selective NMDA GluN2B antagonist Ro25-6981 attenuates neurodegeneration in spinocerebellar ataxia...

An author correction published by Sun, Schulte, Gasser, and colleagues in npj Parkinson’s Disease updates the refined genetic associations tied to Parkinson’s disease susceptibility. The...

A new study in npj Parkinson’s Disease describes a machine learning approach for identifying individuals with Parkinson’s disease who are at heightened risk of falling. The work presents a...

Researchers report that β2 adrenergic receptors help direct neutrophil behavior after myocardial infarction, identifying a mechanism that shapes cardiac immune responses during ischemic injury....

A preclinical-to-early translational development in reproductive medicine suggests securinine, a natural alkaloid, can boost small ovarian follicle growth when delivered via intraovarian...

A high-throughput strategy targeting MDM2 is presented as a potential way to overcome radiation resistance in uveal melanoma, a cancer where durable control remains difficult. The approach focuses...

Final overall survival data from the phase 3 ROSELLA trial show relacorilant (Lifyorli) plus nab-paclitaxel improved outcomes in platinum-resistant ovarian cancer, with results presented at the...

BioNTech and SynOx Therapeutics both moved to a U.S. FDA path for two tumor types as newly published trial data met key goals. The development raises the competitive stakes in oncology, where...

GSK outlined plans for five phase 3 studies for a gynecological cancer antibody-drug conjugate (ADC) licensed from Hansoh Pharma, after sharing early positive data. The company’s expansion to...

Two neuroscience and hematology-focused companies pushed IPO momentum as Seaport Therapeutics and Hemab Therapeutics filed for listings, with Kailera expected to price soon. The filings add to...

Researchers reported a high-throughput strategy targeting MDM2 to overcome radiation resistance in uveal melanoma, aiming at one of the central barriers to durable responses. The approach focuses...

Researchers unveiled allogeneic CD19 CAR T cells engineered with an anti-rejection CD70 CAR to address two key hurdles: antigen escape and alloimmune rejection. The concept combines an attack...

A new diagnostic imaging technique using lacrimal gland color Doppler ultrasonography could move Sjögren’s syndrome detection earlier, according to researchers behind the approach. The report...

Two separate Parkinson’s-focused technology updates moved machine learning and deep learning toward practical clinical use. One study reported a machine learning method to classify people with...

A development-focused report argues that improving preclinical-to-clinical translation requires more than candidate selection—it depends on how safety and predictability data are generated. It...

A report says CDC leadership delayed the release of an analysis intended to show COVID vaccines reduced severe illness, after acting CDC director Dr. Jay Bhattacharya raised concerns about...

Relacorilant (Lifyorli) plus nab-paclitaxel delivered a survival benefit in platinum-resistant ovarian cancer, with final overall survival results from the phase 3 ROSELLA study (NCT05257408)...

GSK moved to expand late-stage development of its gynecological cancer antibody-drug conjugate (ADC) licensed from Hansoh Pharma, outlining a plan for five Phase 3 studies. The update follows...