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Ivermectin Mass Drug Administration Cuts Malaria Infections in Kenya
A landmark cluster-randomized trial in Kwale, Kenya, demonstrated that monthly mass administration of ivermectin to children aged 5–15 reduced new malaria infections by 26%, supplementing existing...
New Pathways Illuminate Mitophagy Initiation in Parkinson’s Disease
University of Vienna researchers decoded molecular mechanisms of mitophagy initiation via transmembrane cargo receptors BNIP3 and NIX, unveiling hierarchical flexibility in autophagy machinery....
Abivax Soars on Phase III Ulcerative Colitis Success and $747 Million Offering
Abivax shares surged dramatically after Phase III results for obefazimod, an oral ulcerative colitis drug, exceeded expectations, catalyzing a heavily oversubscribed U.S. offering initially set at...
FDA Probes Death Linked to Sarepta’s Duchenne Gene Therapy Elevidys
The FDA is investigating the June 7 death of an 8-year-old Brazilian boy receiving Sarepta’s Duchenne muscular dystrophy gene therapy Elevidys amid voluntary shipment suspensions. Sarepta and...
Bipartisan Bill Pushes Medicare Advantage Payment Parity with Traditional Medicare
U.S. legislators introduced the Prompt and Fair Pay Act mandating that Medicare Advantage plans reimburse providers at rates equal to traditional Medicare and expedite claim payments. This...
Selective Estrogen Receptor Degrader Vepdegestrant Outshines Fulvestrant in Breast Cancer
New data reveal that vepdegestrant, a PROTAC-based selective estrogen receptor degrader, demonstrates superior efficacy over fulvestrant in advanced ER-positive, HER2-negative breast cancer...
Microbiota’s Influence Emerges in Radiotherapy-Driven Cancer Immunity
Recent research highlights the critical role of the gut microbiome in shaping antitumor immune responses elicited by radiotherapy. Modulations in microbiota composition affect tumor...
Agrivoltaics Enhances Photosynthesis Mitigating Dryland Heat Stress
A study published in npj Sustainable Agriculture demonstrates that integrating photovoltaic solar panels with crop cultivation (agrivoltaics) alleviates midday photosynthetic depression in dryland...
Long-Read Sequencing Unveils Expansive Microbial Diversity in Terrestrial Habitats
Leveraging genome-resolved long-read sequencing, researchers uncovered unprecedented microbial diversity within terrestrial ecosystems, revealing thousands of novel genomes and metabolic pathways....
Abivax Surges on Ulcerative Colitis Data – Raises $747.5M in Nasdaq Offering
Abivax has delivered a remarkable surge in its shares following positive Phase III clinical data for obefazimod, its oral ulcerative colitis treatment. The positive data drove overwhelming...
FDA Investigates Sarepta’s Elevidys Following Pediatric Death – Safety Concerns Mount
The FDA is conducting a probe into the June death of an 8-year-old Brazilian boy who received Sarepta’s Elevidys gene therapy for Duchenne muscular dystrophy (DMD). The investigation follows two...
GSK’s Blenrep Scores European, Canadian Approvals – US Market Waits
GSK’s antibody-drug conjugate Blenrep has secured regulatory approvals as a second-line treatment in Europe and Canada, signaling a comeback for the drug in multiple myeloma therapies. Despite...
Machine Learning Deciphers Sorghum’s Genetic Mold Resistance
Researchers have applied machine learning techniques to unravel the complex genetic architecture behind sorghum's resistance to grain mold, one of the crop's most destructive diseases. This...
Parkinson’s Advances: Theta-Frequency DBS and Microbiota Transplants Show Promise
New therapeutic strategies for Parkinson’s disease emerge from studies examining neural modulation and gut microbiome interventions. Deep brain stimulation at theta frequencies improved cognitive...
Flexible Organic Electrochemical Transistors Achieved Through Electropolymerized PEDOT
A breakthrough in flexible electronics technology has been achieved by developing durable organic electrochemical transistors using electropolymerized poly(3,4-ethylenedioxythiophene) (PEDOT)....
Innovations in Sustainable Agriculture: Agrivoltaics and Bio-Based Farming Solutions
Sustainability initiatives gain momentum with research showing agrivoltaics enhancing photosynthesis under dryland heat conditions and collaborative European efforts to promote bio-based farming...
Long-Read Sequencing Unveils Unprecedented Microbial Diversity In Terrestrial Ecosystems
A landmark investigation using long-read genome sequencing has exposed extensive and previously hidden microbial diversity across terrestrial habitats. This technology enables high-resolution...
New Insights Into Plant Immunity And Growth Control Via Root N-Hydroxypipecolic Acid Circuit
Researchers have identified a novel root-based regulatory circuit involving N-hydroxypipecolic acid that coordinates immune responses and development in Arabidopsis shoots. Published in Nature...
FDA Investigates Death Linked to Sarepta’s Elevidys Gene Therapy
The FDA has launched an investigation into the recent death of an eight-year-old Brazilian boy who received Sarepta Therapeutics' Duchenne muscular dystrophy gene therapy, Elevidys, which has been...
GSK’s Blenrep Returns With Approvals Abroad but Faces U.S. Hurdles
GSK's antibody-drug conjugate Blenrep has secured second-line approvals in Europe and Canada, marking a regulatory comeback for the targeted therapy. However, U.S. approval remains postponed due...