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AlphaFold database expands: Millions of protein complexes released
EMBL‑EBI, Google DeepMind, NVIDIA and Seoul National University released a vast set of AI‑predicted protein complex structures into the AlphaFold Database. The consortium published millions of...
Structure’s oral GLP‑1 shows injectable‑like efficacy – 44‑week Phase 2
Structure Therapeutics reported Phase 2 data showing its oral GLP‑1 agonist aleniglipron produced about 16% placebo‑adjusted weight loss at 44 weeks. The company plans to advance the candidate...
Masked ADC posts responses in CRC – partnership fallout follows
CytomX disclosed Phase 1 expansion data for its masked antibody‑drug conjugate Varseta‑M showing objective response rates of roughly 20–32% in late‑line metastatic colorectal cancer and...
BioMarin pauses Voxzogo dosing after hip safety signal
BioMarin halted dosing for certain patients in two mid‑stage Voxzogo (vosoritide) studies after independent trials flagged cases of slipped capital femoral epiphysis (SCFE). The company said the...
ARPA‑H awards $9.3M to BioCurie: building AI‑driven gene therapy manufacturing
ARPA‑H granted BioCurie up to $9.3 million to develop an AI‑powered digital platform for scalable gene therapy process development. BioCurie will integrate machine learning, modeling and...
Trenchant and Invetech to commercialize AutoCell: automated point‑of‑care CGT manufacturing
Trenchant BioSystems agreed with Invetech to develop and commercialize the AutoCell fully automated cell and gene therapy (CGT) manufacturing platform. Internal and independent data indicate...
Federal judge stays RFK Jr. vaccine actions: ACIP votes and schedule changes paused
A federal judge in Massachusetts stayed votes taken by Health and Human Services Secretary Robert F. Kennedy Jr.’s reconstituted Advisory Committee on Immunization Practices (ACIP), paused the...
Mayo Clinic engineers milk‑derived nanoparticles for targeted cholangiocarcinoma gene therapy
Mayo Clinic researchers reported a targeted gene‑delivery platform that uses milk‑derived nanoparticles to deliver precision therapeutics to cholangiocarcinoma tumors. The preclinical study showed...
Illumina and Veritas form preventive genomics consortium: whole‑genome sequencing for routine care
Illumina and Veritas Genetics launched a consortium to integrate whole‑genome sequencing into preventive healthcare pathways and create a consented clinical‑genomics dataset. Illumina will supply...
CirCode clears FDA IND for circular RNA therapy trial in the US
CirCode Biomed, a China‑based startup developing circular RNA therapeutics, received FDA clearance to begin a US clinical trial for its circular RNA candidate. The IND greenlight marks one of the...
Judge stays HHS vaccine overhaul — ACIP appointments and schedule frozen
A federal judge in Boston has issued a stay on major elements of Health Secretary Robert F. Kennedy Jr.’s overhaul of U.S. childhood vaccine policy, pausing 13 ACIP appointments and removing the...
Structure’s oral GLP‑1 posts 16% weight loss — company eyes Phase 3
Structure Therapeutics reported Phase 2 data showing its oral GLP‑1 candidate aleniglipron produced an average 16% body-weight reduction at 44 weeks, a result the company says approaches...
CytomX masked ADC shows responses in late‑line colorectal — shares rally
CytomX released expansion‑cohort results for its masked, conditionally activated antibody‑drug conjugate Varseta‑M in late‑line metastatic colorectal cancer, reporting response rates between 20%...
BioMarin halts Voxzogo dosing after hip‑related safety signal
BioMarin announced it will stop dosing certain patients in two mid‑stage trials of Voxzogo following reports of slipped capital femoral epiphysis (SCFE) in independent studies. The company flagged...
ARPA‑H backs AI‑led gene‑therapy manufacturing platform — $9.3M award
ARPA‑H awarded BioCurie up to $9.3 million to develop an AI‑driven, scalable manufacturing platform for viral and non‑viral gene therapies. The program will integrate machine learning,...
Trenchant, Invetech partner to commercialize fully automated CGT platform
Trenchant BioSystems struck an engineering and development collaboration with Invetech to advance its AutoCell platform toward commercialization, targeting fully automated, point‑of‑care cell and...
Illumina and Veritas launch preventive genomics consortium — WGS enters care
Illumina and Veritas Genetics have formed a preventive genomics consortium to bring whole‑genome sequencing into proactive healthcare, offering an opt‑in program that combines Illumina’s...
CirCode clears FDA to test circular RNA therapy in U.S. trial
CirCode Biomed received FDA clearance to begin a U.S. clinical trial of its circular RNA therapeutic, marking a first test of the circular RNA modality in the American regulatory environment. The...
Unixell gains FDA IND for iPSC‑derived allogeneic cell therapy in epilepsy
Shanghai‑based Unixell Biotech received FDA clearance to start a Phase 1 trial of UX‑GIP001, an iPSC‑derived, allogeneic cell therapy for focal epilepsy resistant to drugs. The first‑in‑human...
Roche inks Nvidia deal to accelerate AI drug and diagnostic factory
Roche announced an expanded partnership with Nvidia to bolster its AI 'factory' for drug and diagnostic development, aiming to accelerate model training, molecular design, and diagnostic pipelines...