Latest Biotech News

NewBiologix and Synastra Biotechnology signed an agreement to develop a stable producer cell line for Synastra’s investigational Duchenne muscular dystrophy gene therapy. NewBiologix will use its...

A new in vitro study reported that 1,5-pentanediamine—detectable in blood from patients colonized with carbapenem-resistant Klebsiella pneumoniae—can weaken CD19 CAR-T cell function. Researchers...

Chinese researchers reported a machine-learning decision system to predict distant metastasis in a rare, aggressive primary liver cancer form using retrospective data. Published in Cancer Cell...

A new prediction model in high-grade glioma used combined radiomics and pathomics to forecast one-year progression. Published in Annals of Clinical and Translational Neurology, the study targets a...

Radiologists and AI researchers reported a high-resolution CT radiomics model that predicts invasiveness in pure ground-glass lung adenocarcinoma. The work, led by Tianjin Chest Hospital, combines...

Researchers at the University of Lisbon and Universitat Politècnica de Catalunya introduced a mathematical “replicator framework” that predicts bacterial vaginosis with 94% accuracy, aligning with...

Computational chemists reported machine-learning and free-energy-guided design of new tuberculosis KasA inhibitors. The study, published in Molecular ... , describes a fragment-based recombination...

A real-world analysis found that severe hypoglycemia and impaired awareness can reduce quality of life in continuous glucose monitoring (CGM) users. The report underscores that CGM adoption does...

A Chinese team reported a microfluidic technique designed to improve CAR-T cell transduction efficiency at low viral doses. Published in the study described here, the method aims to compress the...

NewBiologix and Synastra Biotechnology announced a collaboration to advance rAAV manufacturing for Synastra’s investigational Duchenne muscular dystrophy program, centered on developing a stable...

A Novartis and Ionis pelacarsen setback is reigniting questions about the next steps for lipoprotein(a)–lowering therapies and the broader cardiovascular strategy built around them. The report...

A review challenges the performance of the FDA-cleared Lumipulse G plasma p-tau217/Aβ1−42 ratio for Alzheimer’s diagnosis, arguing the metric shows “flaws” in practice. Researchers Christian...

Researchers report that 1,5-pentanediamine—found in the blood of patients colonized with carbapenem-resistant Klebsiella pneumoniae—can weaken CD19 CAR-T cell activity in vitro. The study,...

Case Western Reserve University researchers unveiled a mechanistic roadmap for multivalent mRNA–exosome vaccines designed to convert “cold” tumors into “hot” immunologically active lesions. The...

A South Korea–based team engineered a new bispecific TCR-like antibody targeting the PRAME complex, reporting laboratory validation that could expand cancer immunotherapy to patients previously...

Whole-genome sequencing identified genetic predictors of rifabutin susceptibility in multidrug-resistant tuberculosis, pointing to a potential path toward more precise drug selection. The study,...

A real-world assessment links severe hypoglycemia and impaired awareness to lower quality of life in continuous glucose monitoring (CGM) users, reframing how clinicians evaluate CGM benefits...

Researchers at the University of Warwick, with clinicians from University Hospital North Midlands NHS Trust and Imperial College London, used digital twin technology to evaluate a proposed airway...

A study in Science Translational Medicine reports that suppressing microRNA-224 (miR-224) can prevent decline in heart function in mouse models of pulmonary arterial hypertension. Researchers used...

FDA has approved Ionis Pharmaceuticals’ zilganersen (Zanvastro) as the first disease-modifying therapy for ultra-rare Alexander disease. The approval marks a milestone for a rare neuroscience...