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CSL Announces Vaccine Spin-Off and Significant Workforce Reductions
Australian pharmaceutical company CSL revealed a major restructuring plan involving spinning off its influenza vaccine business, Seqirus, into a standalone company and cutting up to 15% of its...
FDA Rejects PTC Therapeutics' Friedreich’s Ataxia Drug Vatiquinone
The FDA issued a complete response letter for PTC Therapeutics’ 15-lipoxygenase inhibitor, vatiquinone, declining approval for Friedreich’s ataxia due to insufficient evidence of efficacy. Despite...
Hybrid AI Model Enhances Mammogram Interpretation Accuracy
Dutch researchers published a groundbreaking study in Radiology demonstrating that a hybrid reading strategy combining artificial intelligence with radiologist assessment improves mammogram...
Spray Drying Platform Converts IV Biologics into Injectable Forms
Stanford University researchers have developed an innovative spray drying formulation platform enabling the conversion of traditionally intravenous protein therapeutics into stable,...
Advances in Brain Waste Clearance Illuminate Health Implications
Neuroscientist Laura Lewis and colleagues at MIT have visualized, using real-time imaging, pulsatile cerebrospinal fluid flow in the brain’s glymphatic system that clears toxic waste products such...
Graphene Stimulation Accelerates Brain Organoid Maturation for Disease Modeling
Researchers at UC San Diego have developed Graphene-Mediated Optical Stimulation (GraMOS), a novel non-genetic method that uses graphene to convert light into electrical cues, accelerating the...
Xoma’s Latest Acquisition of Biotech Mural Oncology Highlights Industry Consolidation
Xoma Royalty, a drug royalty specialist, has acquired struggling biotech Mural Oncology for approximately $36 million, marking its fourth acquisition since June 2025. This move continues Xoma’s...
FDA Lifts Clinical Hold on Rocket Pharmaceuticals’ Danon Disease Gene Therapy
The FDA has lifted a clinical hold on Rocket Pharmaceuticals' pivotal Phase II trial for the gene therapy RP-A501 targeting Danon disease, after implementing protocol adjustments including dose...
Novel Spray Drying Platform Enables High-Concentration Injectables from Protein Therapeutics
Stanford University researchers have developed a spray drying technique incorporating a glassy surfactant excipient (MoNi) to convert intravenous protein-based therapeutics into high-concentration...
New Insights into Lung Large Cell Neuroendocrine Carcinoma Drive Diagnostics and Treatment
A comprehensive study published in Nature Communications elucidates the molecular and clinical features of pulmonary large cell neuroendocrine carcinoma (LCNEC), a rare and aggressive lung cancer...
AI-Integrated Lab-in-the-Loop Platforms Expand Biopharma Drug Discovery Capacity
Ginkgo Bioworks has partnered with Inductive Bio and Tangible Scientific to launch a unified AI-driven lab-in-the-loop drug discovery workflow aiming to streamline high-throughput experimentation,...
Breakthrough Study Links Brain Inflammation from High-Salt Diet to Hypertension
A pivotal study from McGill University demonstrates that excessive salt intake induces brain inflammation driving increases in blood pressure. This research challenges traditional kidney- and...
Multi-Ancestry Genomic Study Reveals Novel Genetic Loci Linked to Keloid Disease
An unprecedented multi-ancestry meta-analysis has identified novel genetic susceptibility loci associated with keloid formation, a complex fibroproliferative skin disorder. By integrating diverse...
AI-Powered Fluorescent Probes Illuminate Incretin Receptors in Pancreas and Brain
Researchers have engineered fluorescent dual agonist probes targeting GLP1R and GIPR receptors, enabling unprecedented visualization of incretin hormone action within pancreatic and neural...
Major Restructuring at CSL Includes Seqirus Spin-Off and Workforce Reduction
Australian pharma giant CSL announced a comprehensive restructuring plan involving the separation of its vaccine subsidiary Seqirus as an independent publicly listed company by mid-2026, alongside...
FDA Lifts Clinical Hold on Rocket Pharmaceuticals Gene Therapy Trial
The FDA has approved Rocket Pharmaceuticals to resume its pivotal Phase 2 gene therapy trial for Danon disease, a rare genetic disorder affecting multiple organs including the heart. The trial had...
Viking Therapeutics’ Oral Obesity Drug Data Sparks Investor Concern
Viking Therapeutics reported Phase 2 data for its oral obesity drug VK-2735 showing statistically significant weight loss of up to 12.2% after 13 weeks at the highest dose. However, the study...
CSL’s Vaccine Unit Spin-Off and Workforce Reductions Unveiled
Australian biopharma CSL announced a strategic overhaul involving the separation of its influenza vaccine business, Seqirus, into a standalone company projected to be completed by June next year....
Breakthroughs in Epigenomic and Single-Cell Technologies
Emerging companies and academic groups are advancing epigenomic analysis and single-cell technologies to enhance precision medicine and biological insights. Epigenica, a Swedish startup, is...
Advances in Neurodegenerative Disease Research and Therapies
Research continues to illuminate mechanisms and treatments for neurodegenerative diseases. Eli Lilly plans to replace Anne White, head of its neuroscience division, after her retirement in...