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UniQure’s Gene Therapy Slows Huntington’s Disease by 75%
UniQure recently reported positive results from its pivotal Phase I/II study of AMT-130, a gene therapy aimed at treating Huntington’s disease. The high-dose treatment demonstrated a statistically...
FDA Approves Lilly’s Oral SERD for Advanced Breast Cancer Subtype
The FDA has approved Eli Lilly’s Inluriyo (formerly imlunestrant), an oral selective estrogen receptor degrader (SERD), for treating adults with metastatic, estrogen receptor-positive,...
Hansa Biopharma’s Imlifidase Shows Promise for Kidney Transplant Patients
Hansa Biopharma’s imlifidase, an antibody-cleaving enzyme, has yielded positive data from a pivotal U.S. Phase III trial in highly sensitized kidney disease patients. The drug rapidly removes...
Revolutionary Bridge Recombinase Technology Enables Megabase-Scale Human Genome Editing
Researchers at the Arc Institute have developed and optimized bridge recombinases, versatile RNA-guided enzymes capable of large-scale genome rearrangements in human cells at efficiencies up to...
Unprecedented AI-Driven Gene Therapy for Cancer and Immune Cell Design
The Arc Institute unveiled 'Germinal', an AI-driven platform combining AlphaFold-Multimer gradients and antibody language models to design epitope-targeted antibodies with reduced experimental...
Integration of AI Accelerates Laboratory Nanoparticle Drug Delivery Design
Biomedical engineers at Duke University have pioneered a platform that merges automated wet lab protocols with sophisticated artificial intelligence to revolutionize nanoparticle design for drug...
Tailored Bacteriophage Therapies Combat Antimicrobial-Resistant Infections
In a major advance against drug-resistant pathogens, researchers from Monash University and The Alfred Hospital engineered bespoke bacteriophage cocktails targeting multidrug-resistant bacterial...
UniQure’s AMT-130 Gene Therapy Achieves First Successful Huntington’s Treatment Milestone
UniQure’s AMT-130 therapy marks a historic milestone as the first intervention to demonstrate a marked 75% slowing in Huntington’s disease progression over three years, according to pivotal...
AI Advances Enable Highly Precise, Kinetically Controlled Protein Therapeutics
Scientists led by David Baker’s lab at the University of Washington developed a generalizable molecular switch design that precisely modulates protein-protein binding kinetics, increasing...
Gene Therapy Milestone: Uniqure's Huntington's Treatment Slows Disease Progression 75%
Uniqure has announced positive top-line data from the pivotal Phase I/II study of its gene therapy AMT-130 for Huntington's disease, demonstrating a statistically significant 75% slowing in...
Novel Bridge Recombinase System Enables Megabase-Scale Human Genome Editing
Researchers at the Arc Institute have developed a universal bridge recombinase platform that expands gene editing capabilities beyond small mutations to enable large-scale genomic rearrangements...
FDA Approves Lilly's Oral SERD Inluriyo for ESR1-Mutated Breast Cancer
The FDA has cleared Eli Lilly's oral selective estrogen receptor degrader (SERD) Inluriyo (formerly imlunestrant) for treatment of adults with metastatic, estrogen receptor-positive, HER2-negative...
Microchip-Based Peptide Sequencing Enters Commercialization Pathway
Pumpkinseed, a Stanford University spinout, is advancing its silicon chip technology that sequences peptides and analyzes immune cell functionality using Raman spectroscopy. Its platform enables...
Hansa Biopharma's Imlifidase Shows Promise in Kidney Transplant Phase III Trial
Hansa Biopharma has reported positive Phase III trial results for imlifidase, an enzyme that rapidly removes anti-HLA antibodies, enabling highly sensitized kidney transplant patients to receive...
Innovative Peptide Nets Offer New Hope Against Antibiotic-Resistant Bacteria
Biotechnologist Rachel Ee of the National University of Singapore has developed short self-assembling peptides that form microscopic nets in response to bacterial presence, trapping and killing...
UniQure’s AMT-130 Gene Therapy Clinically Validated to Slow Huntington's Disease
UniQure has achieved a pivotal success in Huntington's disease (HD) gene therapy with its AMT-130 candidate, demonstrating a significant 75% reduction in disease progression at 36 months in a...
Lila Sciences Raises $235M to Accelerate AI-Powered Scientific Discovery
Lila Sciences secured $235 million in a Series A round led by Braidwell and Collective Global to scale its AI-driven scientific research platform. The company integrates generative AI, robotics,...
UniQure Gene Therapy’s Pivotal Data Fuels Hope for Huntington's Disease Approval
New clinical data from UniQure's AMT-130 gene therapy reveal a substantial slowing of Huntington's disease progression by 75% over three years in treated patients, meeting the primary composite...
Advances in CRISPR Screening Identify Genetic Tweaks to Boost CAR T Cell Therapies
Mass General Brigham and Broad Institute researchers deployed comprehensive CRISPR screening across the T cell lifecycle to discover gene knockouts enhancing CAR T cell proliferation, persistence,...
uniQure’s Gene Therapy Slows Huntington’s Disease Progression by 75%
UniQure announced positive topline results from its pivotal Phase I/II trial of AMT-130, a gene therapy for Huntington’s disease, demonstrating a statistically significant 75% slowing in disease...