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Biotech ETFs rally: XBI, IBB, ARKG reassert momentum
Biotech-focused exchange-traded funds have posted double-digit gains over the past six months, with XBI up roughly 34%, IBB up ~25% and ARKG surging about 42% in the recent stretch. Analysts...
Walgreens frames pharmacies as strategic partners for specialty care
Walgreens and other community pharmacies are positioning themselves as strategic partners for biopharma to improve specialty medication adherence and patient support, driven by rising advanced...
DNBSEQ exome showdown: four capture platforms benchmarked
Researchers compared four exome capture platforms using the DNBSEQ high-throughput sequencer to benchmark coverage, on-target rates and variant-calling performance. The study provides sequencing...
Agile site networks: sponsors told to vet to speed oncology trials
Industry reports promoted agile clinical site networks as a way to accelerate oncology trials by aligning sponsors, trial sites and investigators on common operational goals. The piece advised...
3D-printed tumor scaffolds: new platform for glioblastoma drug screens
Researchers developed 3D-printed scaffold models to improve glioblastoma drug screening, enabling more physiologically relevant tumor architectures than traditional 2D cultures. The platform,...
Novartis bets $12 billion on RNA drugs — Avidity takeover
Novartis announced its agreement to acquire Avidity Biosciences for roughly $12 billion in cash, a deal that hands Novartis a portfolio of RNA-based candidates targeting neuromuscular diseases....
Flagship launches Expedition Medicines: AI hunts elusive targets
Flagship Pioneering launched Expedition Medicines, a startup using artificial intelligence to map the chemistry of small‑molecule binding against proteins historically deemed undruggable....
Town Hall raises $440M fund: AI for underserved healthcare
Town Hall Ventures closed a $440 million fund to back startups applying artificial intelligence to expand healthcare access and outcomes for underserved populations. The firm positioned the fourth...
Long‑acting injectable buprenorphine... lowers inpatient burden
A recent study found that long‑acting injectable formulations of buprenorphine reduce the need for inpatient services among patients with opioid use disorder, shifting care from hospitals to...
Wastewater rotavirus RNA mirrors US infection and vaccine uptake
Researchers demonstrated that rotavirus RNA levels detected in wastewater correlate with population‑level infection rates and vaccination coverage across the United States. The study used...
Metagenomics reveals strain‑level pneumonia pathogens
A team led by Zhou et al. used metagenomic sequencing to identify strain‑level diversity among bacterial pathogens causing pneumonia, improving resolution beyond species identification. The study...
AI algorithms validated for urothelial tumor classification
A multicenter consortium validated artificial‑intelligence models for classifying urothelial neoplasms on digital pathology slides, reporting robust performance across institutions. The research...
CAR‑T and CAR‑NK therapies reshape AML research
Recent reviews and studies synthesize advances in CAR‑T and CAR‑NK cell therapies for acute myeloid leukemia (AML), outlining engineered strategies to overcome antigen heterogeneity and myeloid...
3D‑printed scaffolds boost glioblastoma drug screening
Researchers developed 3D‑printed scaffold models to better mimic glioblastoma microenvironments and improve preclinical drug screening fidelity. The scaffolds preserved tumor heterogeneity and...
Targeting FBXL5 reverses oxaliplatin resistance in colorectal cancer
A study by Wang et al. identified FBXL5 as a molecular driver of oxaliplatin resistance in iron‑rich colorectal cancers and showed that targeting FBXL5 sensitizes tumors to chemotherapy by...
Novartis to buy Avidity for $12B – Scores RNA neuromuscular pipeline
Novartis agreed to acquire Avidity Biosciences in a cash transaction that values the RNA-focused developer at about $12 billion. The deal, announced Sunday, buys Novartis three late-stage programs...
Nanopore cfDNA test spots tissue origin and pathogens in ICU patients
Researchers unveiled a nanopore sequencing workflow that analyzes plasma cell‑free DNA to report both tissue‑of‑origin signals and pathogen presence from a single blood draw. The approach was...
Metagenomic sequencing unmasks pneumonia pathogens at strain level
A team led by Zhou et al. published a strain‑level metagenomic sequencing study of pneumonia pathogens, demonstrating the ability to resolve intra‑species variation directly from clinical samples....
CAR‑based cell therapy expands into AML — CAR‑T and CAR‑NK advances
Researchers reviewed recent preclinical and early clinical work advancing CAR‑T and CAR‑NK approaches against acute myeloid leukemia (AML). The report synthesizes new antigen targets, engineering...
Nanotherapeutics program reprograms macrophages to tackle atherosclerosis
A preclinical study from Xu, Zhang and Yu outlines nanoparticle strategies designed to modulate macrophage behavior in atherosclerotic plaques. Investigators report targeted delivery systems that...