10x Genomics announced three clinically focused collaborations and plans to open a CLIA‑certified lab in early 2027 as it seeks to translate single‑cell and spatial platforms into diagnostic applications. Partnerships include Dana‑Farber Cancer Institute for solid tumor profiling and the Cancer Research Institute to build a 500‑million‑cell immuno‑oncology dataset; academic collaborators include Penn, Stanford and MSK. The company said datasets will benchmark AI models and identify cellular features predictive of response. Separately, 10x reported preliminary Q4 revenue of $166 million with consumables growth offsetting instrument declines; management emphasized clinical validation and services as key paths to commercial traction for single‑cell and spatial assays.