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Guardant Health, Zephyr AI partner: multimodal biomarkers in focus
Guardant Health and Zephyr AI announced a strategic partnership to combine Guardant’s multimodal molecular datasets with Zephyr’s AI analytics to accelerate discovery of genomic biomarkers for...
MIT’s BoltzGen opens AI drug design: expands the druggable universe
An MIT research team released BoltzGen, an open‑source generative model that moves from structural prediction toward generalizable therapeutic design across modalities including small molecules,...
MapLight prices $250M IPO — funding Cobenfy challenger
MapLight Therapeutics filed for and priced a $250 million IPO to develop a competitor to Bristol Myers Squibb’s schizophrenia drug Cobenfy. The proceeds will finance clinical development of the...
Revvity posts modest growth as newborn screening and immunodiagnostics lead
Revvity reported third‑quarter results with 2% overall revenue growth to $698.9 million and a 3% rise in diagnostics revenue driven by newborn screening and immunodiagnostics. The company cited...
Expedition Medicines launches: AI startup targets ‘undruggable’ proteins
Flagship Pioneering-backed Expedition Medicines launched with an AI‑driven platform that analyzes proteome chemistry to design small molecules for targets considered undruggable. The company...
Novartis buys Avidity for $12B — expands RNA neuromuscular push
Novartis agreed to acquire Avidity Biosciences for roughly $12 billion, adding three late-stage RNA-based programs aimed at muscular dystrophies and related neuromuscular diseases. The Swiss...
Hemab raises $157M — builds 'ultimate' coagulation disorders company
Hemab Therapeutics closed a $157 million financing to advance a pipeline targeting underserved bleeding disorders, including two clinical-stage candidates. The round was led by Sofinnova Partners...
Novo re-engages and closes $4.7B MASH deal — deal talks resumed
Novo Nordisk returned to the table and completed a roughly $4.7 billion acquisition of MASH drug developer Akero Therapeutics after earlier walking away from talks. The transaction consolidates...
Flagship launches Expedition Medicines — AI to target 'undruggable' proteins
Flagship Pioneering launched Expedition Medicines, an AI-driven startup that claims to learn chemistry rules to bind historically undruggable proteins. The company announced an R&D alliance with...
GSK signs $357M pact with French biotech — prostate ADC preclinical deal
GSK struck a $357 million agreement with French biotech Syndivia to access a preclinical antibody-drug conjugate (ADC) program for prostate cancer. The deal covers preclinical work and potential...
Town Hall raises $440M — VC backs AI to improve healthcare access
Town Hall Ventures closed a $440 million fund to invest in startups using AI to expand healthcare access and outcomes for underserved populations. The firm targets companies that combine clinical...
Wastewater and metagenomics sharpen infectious-disease surveillance
Two studies highlight advances in infectious-disease surveillance: one used metagenomic sequencing to resolve strain-level pneumonia pathogens, and another linked rotavirus RNA trends in...
AI and single-cell tools refine molecular classification and discovery
New computational tools advanced by two research teams promise to improve diagnostic classification and single-cell analysis workflows. A multi-institution validation showed AI models can classify...
New targets revive platinum sensitivity — paths to overcome resistance
Preclinical studies identified actionable routes to reverse resistance to platinum chemotherapy: targeting FBXL5 sensitized iron-rich colorectal tumors to oxaliplatin via ferroptosis mechanisms,...
Preclinical platforms reveal therapy leads in brain and breast cancer
Two laboratory advances aim to improve preclinical translation: a 3D-printed scaffold model refined glioblastoma drug screening to better mimic tumor microenvironments, and a Cell paper showed...
Novartis goes big for neuromusculars: $12B Avidity buy
Novartis moved to acquire Avidity Biosciences in a roughly $12 billion deal, adding a trio of late-stage RNA-based programs targeting Duchenne muscular dystrophy, myotonic dystrophy type 1 and...
GSK bets on ADCs: $357M deal for prostate program
GSK struck a pact worth up to $357 million with French biotech Syndivia for a preclinical prostate cancer antibody-drug conjugate (ADC). The agreement, disclosed after a European cancer conference...
Novo’s boardroom drama ends with MASH buy: $4.7B Akero move
Novo Nordisk walked away from earlier acquisition talks for Akero Therapeutics before returning to complete a $4.7 billion purchase of MASH drug developer Akero, according to reporting on the deal...
Flagship launches Expedition Medicines: AI for undruggable proteins
Flagship Pioneering launched Expedition Medicines, an AI-driven startup that claims to learn chemical rules to bind small molecules to historically 'undruggable' protein targets. The company...
Town Hall raises $440M — AI startups targeted at care gaps
Town Hall Ventures closed a $440 million fund to back startups deploying AI to improve healthcare access and outcomes for underserved populations. The fund, the firm’s fourth, signals growing...