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Atrium launches with $270M to pursue RNA therapies for rare cardiac disorders
Atrium Therapeutics emerged from Avidity Biosciences with a $270 million launch financing to pursue two RNA therapy programs targeting rare inherited cardiomyopathies. The spin‑out follows...
Chinese obesity biotech QL Biopharm secures $72M Series C with OrbiMed backing
QL Biopharm closed a roughly $72 million (500 million CNY) Series C financing led by OrbiMed and Qiming Venture Partners to advance late‑stage programs in obesity. The capital infusion will...
Bavarian Nordic CEO Paul Chaplin resigns after failed $3B takeover bid
Paul Chaplin, who led Bavarian Nordic for more than 30 years, announced his departure months after a proposed $3 billion takeover by private equity collapsed last November. The management change...
Novartis tests Rhapsido beyond hives — phase 2 food‑allergy readout posted
Novartis presented phase 2 data indicating its recently approved urticaria drug Rhapsido produced higher response rates in a food allergy cohort across three dose levels. The company framed the...
CAR macrophages breach brain barriers in preclinical lung‑metastasis models
Wake Forest University researchers engineered CAR macrophages (CARMA) that demonstrated brain‑penetrant immunotherapy activity against lung‑cancer brain metastases in preclinical studies. The...
AI pathology under fire: models learn shortcuts instead of biology
A University of Warwick study published in Nature Biomedical Engineering found that AI tools for cancer pathology are prone to “shortcut learning,” where models rely on spurious correlations in...
Close open steps: cell therapy manufacturers race to cut contamination risk
Manufacturers and regulators are pressing to eliminate open manipulations in cell therapy production to reduce contamination risk and scale operations. The article outlines how “open”...
Spain unveils end-to-end spatial‑omics platform: IRB Barcelona ties cores
IRB Barcelona has launched the country’s first end‑to‑end spatial‑omics workflow, uniting core facilities to support academic, clinical and industry users with tissue processing, multiplexed...
FDA offers bonus pay: reviewers to be rewarded for faster drug reviews
FDA Commissioner Marty Makary announced a pilot program that will pay quarterly bonuses to drug reviewers who complete reviews ahead of schedule, according to slides and a staff presentation...
Atrium spins out with $270M: RNA therapies target rare cardiac disorders
Atrium Therapeutics launched with a $270 million financing to advance two RNA therapy candidates for rare inherited cardiac conditions, the company said. Atrium spun out of Avidity Biosciences...
Belzutifan+pembrolizumab cuts relapse risk: LITESPARK‑022 posts Phase 3 disease‑free survival gains
The Phase 3 LITESPARK‑022 trial reported that combining belzutifan, a HIF‑2α inhibitor, with pembrolizumab significantly improved disease‑free survival in high‑risk clear‑cell renal cell carcinoma...
Novartis tests Rhapsido in food allergy — Phase 2 signals
Novartis presented preliminary Phase 2 data evaluating Rhapsido, a drug recently approved for chronic spontaneous urticaria, in food allergy. The company reported that all three investigational...
Viral proteins reveal bacterial 'kill switch' — MurJ locked and defeated
Researchers discovered that unrelated bacteriophages disable the essential bacterial cell‑wall protein MurJ by locking it into a single conformation, halting peptidoglycan assembly and causing...
X‑ray activated platinum complex boosts radiotherapy and immunotherapy response
Researchers reported a platinum complex that is activated by X‑rays to enhance radiotherapy efficacy and amplify anti‑tumor immune responses in preclinical models. The compound operates via a...
Microfluidic chips predict implantation: chemiluminescent metabolic assay for IVF
Researchers unveiled a chemiluminescent microfluidic chip with dielectric wetting valves that non‑invasively measures embryo metabolites to predict implantation potential. The device integrates...
Wearable ultrasound microneedle patch delivers on‑demand gout therapy
A newly reported wearable device combines ultrasound actuation with microneedle drug delivery to provide both immediate and sustained therapy for gouty arthritis. Published in npj Flexible...
Atrium spins out with $270M to back RNA cardiac programs
Atrium Therapeutics launched with $270 million in initial financing to develop RNA therapies for rare inherited cardiac conditions. The company spun out from Avidity Biosciences after Avidity’s...
FDA pilots bonuses to speed drug reviews — Makary leads change
FDA Commissioner Marty Makary announced a pilot program to pay bonuses to drug reviewers who complete reviews ahead of schedule, with the first quarterly payments expected in August. The plan ties...
Belzutifan plus pembrolizumab extends disease-free survival in kidney cancer
The phase 3 LITESPARK-022 trial reported that combining belzutifan, a HIF-2α inhibitor, with pembrolizumab significantly improved disease-free survival in high-risk clear cell renal cell carcinoma...
Novartis’ Rhapsido shows Phase 2 signal in food allergy
Novartis reported Phase 2 data indicating its recently approved hives drug, Rhapsido, produced higher response rates across three doses in a food allergy study. Company investigators presented...