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Lonza and Qurient Therapeutics Partner on Dual-Payload ADC Development
Lonza’s Synaffix platform entered a licensing agreement with South Korea’s Qurient Therapeutics to develop a clinical-stage dual-payload antibody-drug conjugate (ADC) targeting solid tumors. The...
Claritas Rx Launches Access Analytics to Accelerate Market Insights
Claritas Rx unveiled its Access Analytics platform to address fragmented data in market access operations for commercial life science companies. The software consolidates real-time data from...
Uniqure Wins FDA Path with Gene Therapy for Huntington’s Disease
Uniqure announced a landmark success with its gene therapy AMT-130 demonstrating a 75% slowing of Huntington’s disease progression at 36 months, based on a pivotal Phase I/II study. The therapy...
FDA Approves Eli Lilly’s Oral SERD for Advanced Breast Cancer
The FDA granted approval to Eli Lilly’s Inluriyo (imlunestrant), an oral selective estrogen receptor degrader (SERD) for advanced breast cancer patients harboring ESR1 mutations. The decision is...
Hansa Biopharma’s Imlifidase Succeeds in Phase 3 Kidney Transplant Trial
Hansa Biopharma reported positive Phase 3 trial results for imlifidase, an enzyme that cleaves antibodies to enable kidney transplants for highly sensitized patients on dialysis. The trial showed...
CRISPR Gene Editing Enhances CAR T Cell Therapies for Multiple Myeloma
Researchers at Mass General Brigham and the Broad Institute have employed CRISPR screening to identify gene knockouts that improve T cell function and persistence in chimeric antigen receptor...
AI and Automation Accelerate Nanoparticle Design for Drug Delivery
Biomedical engineers at Duke University developed an integrated AI-driven platform combining automated wet lab processes with artificial intelligence to rapidly design nanoparticles optimized for...
Revolutionary Single-Cell Live-Seq Workflow Enables Longitudinal Transcriptomic Analysis
Cytosurge and Lexogen have launched a live-cell sequencing workflow integrating FluidFM cytoplasmic sampling and ultra-sensitive RNA library preparation to enable repeated transcriptomic profiling...
Breakthrough in AI-Enabled Gene Editing Kinetics Offers Safer Drug Control
A team at the University of Washington developed a novel protein on/off switch leveraging AI-guided design to facilitate rapid dissociation kinetics, accelerating cytokine signaling modulation by...
Novel Nanocomposites Enhance Electrochemical Supercapacitors
Researchers have engineered a copper oxide and barium oxide (CuO/BaO) nanocomposite exhibiting superior pseudocapacitive performance for next-generation energy storage applications. Synthesized...
Unprecedented Mapping of Robertsonian Chromosome Fusion Sites Illuminates Genome Evolution
Scientists have completed the first telomere-to-telomere sequencing of human Robertsonian chromosomes, identifying precise DNA breakpoints within repeated SST1 sequences where chromosome arms...
Advances in Pancreatic Cancer Treatment and Understanding Tumor Heterogeneity
Recent studies highlight significant progress in pancreatic cancer research, from immune-mediated tumor control via MEK inhibitor atebimetinib combined with chemotherapy to deciphering cellular...
UniQure’s Gene Therapy Slows Huntington’s Disease by 75%
UniQure recently reported positive results from its pivotal Phase I/II study of AMT-130, a gene therapy aimed at treating Huntington’s disease. The high-dose treatment demonstrated a statistically...
FDA Approves Lilly’s Oral SERD for Advanced Breast Cancer Subtype
The FDA has approved Eli Lilly’s Inluriyo (formerly imlunestrant), an oral selective estrogen receptor degrader (SERD), for treating adults with metastatic, estrogen receptor-positive,...
Hansa Biopharma’s Imlifidase Shows Promise for Kidney Transplant Patients
Hansa Biopharma’s imlifidase, an antibody-cleaving enzyme, has yielded positive data from a pivotal U.S. Phase III trial in highly sensitized kidney disease patients. The drug rapidly removes...
Revolutionary Bridge Recombinase Technology Enables Megabase-Scale Human Genome Editing
Researchers at the Arc Institute have developed and optimized bridge recombinases, versatile RNA-guided enzymes capable of large-scale genome rearrangements in human cells at efficiencies up to...
Unprecedented AI-Driven Gene Therapy for Cancer and Immune Cell Design
The Arc Institute unveiled 'Germinal', an AI-driven platform combining AlphaFold-Multimer gradients and antibody language models to design epitope-targeted antibodies with reduced experimental...
Integration of AI Accelerates Laboratory Nanoparticle Drug Delivery Design
Biomedical engineers at Duke University have pioneered a platform that merges automated wet lab protocols with sophisticated artificial intelligence to revolutionize nanoparticle design for drug...
Tailored Bacteriophage Therapies Combat Antimicrobial-Resistant Infections
In a major advance against drug-resistant pathogens, researchers from Monash University and The Alfred Hospital engineered bespoke bacteriophage cocktails targeting multidrug-resistant bacterial...
UniQure’s AMT-130 Gene Therapy Achieves First Successful Huntington’s Treatment Milestone
UniQure’s AMT-130 therapy marks a historic milestone as the first intervention to demonstrate a marked 75% slowing in Huntington’s disease progression over three years, according to pivotal...