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Advances in Continuous Manufacturing Transform Biologics Production
Continuous bioprocessing technologies, such as the XCell ATF system adopted by Enzene Biosciences, are improving monoclonal antibody manufacturing by enabling higher productivity, reduced costs,...
ProKidney’s Cell Therapy Shows Dose-Dependent Kidney Function Benefits in Phase 2
ProKidney's autologous cell therapy rilparencel demonstrated a significant reduction in kidney function decline by 78% in one cohort of diabetic chronic kidney disease patients. Another cohort...
Jasper Therapeutics Slashes Workforce After Drug Trial Setbacks
Following disappointing clinical trial results with its KIT-targeting antibody briquilimab, Jasper Therapeutics is reducing its staff by approximately 50%. The clinical failures included loss of...
Actithera Raises $75M Series A to Advance Radiopharmaceutical Oncology Pipeline
Radiopharmaceutical biotech Actithera closed a $75.5 million Series A round, despite operating as a single-person company during fundraising. The financing will support clinical development of...
Liquid Biopsy and AI Tools Advance Cancer and Genetic Disease Research
Quanterix completed the acquisition of Akoya Biosciences for $127 million, integrating spatial biology and tissue testing technologies to streamline liquid biopsy biomarker discovery and...
Endometriosis Diagnosis Via Salivary MicroRNA Shows Promise
Researchers led by Sofiane Bendifallah developed a non-invasive diagnostic approach for endometriosis using salivary microRNA signatures. This method may overcome the diagnostic delay associated...
Merck Expands Respiratory Pipeline: $10 Billion Verona Acquisition
Merck & Co. has agreed to acquire London-based Verona Pharma for approximately $10 billion, marking its largest deal since 2023. Verona's FDA-approved inhaled drug Ohtuvayre (ensifentrine) is...
Liquid Biopsy Breakthrough: Microbiome RNA Marks Colorectal Cancer
Researchers at the University of Chicago developed a new liquid biopsy test detecting colorectal cancer through methylation modifications in microbiome-derived cell-free RNA in plasma. Utilizing...
Continuous Biologics Manufacturing: Industry Shift to Cost-Efficiency
Biopharmaceutical manufacturers are increasingly adopting continuous manufacturing techniques over traditional fed-batch methods for monoclonal antibody (mAb) production. Studies demonstrate...
ProKidney's Mixed Phase II Results Boost Kidney Disease Therapy Hope
ProKidney Corp. reported mixed data from its Phase II REGEN-007 trial evaluating rilparencel, a cell therapy for chronic kidney disease (CKD) in diabetic patients. In the two-dose cohort,...
Arvinas CEO John Houston to Retire Amid Protein Degrader Program Progress
Arvinas announced CEO John Houston will retire after over eight years steering the company, as its lead PROTAC (proteolysis-targeting chimera) protein degrader program nears a critical development...
Actithera Secures $75.5M Series A To Develop FAP-Targeted Radiopharmaceuticals
Radiopharmaceutical developer Actithera closed a $75.5 million Series A financing round to advance clinical development of small-molecule therapeutics targeting fibroblast activation protein...
FDA Approvals Target Alzheimer’s and Non-Small Cell Lung Cancer Updates
The FDA granted approval for a modified dosing regimen of Eli Lilly’s Alzheimer’s drug Kisunla to reduce risk of brain swelling, aiming to increase physician adoption. Meanwhile, Dizal...
Biopharma Layoffs Surge 32% in First Half 2025 Amid Industry Challenges
The biopharma sector experienced a sharp rise in workforce reductions during the first half of 2025, with 128 reported layoff rounds—32% more than the same period last year. Multiple companies...
New AI Collaborations Accelerate Oncology Drug Discovery
Iambic Therapeutics and Revolution Medicines entered a multi-year partnership integrating Iambic's AI-driven NeuralPLexer platform with Revolution’s proprietary oncology data. The collaboration...
Merck’s $10 Billion Bet on Verona Pharma’s Lung Drug
Merck & Co. has agreed to acquire London-based Verona Pharma for $10 billion, securing the rights to Ohtuvayre, a lung drug recently approved by the FDA for chronic obstructive pulmonary disease...
FDA Approves New Dosing and Tests for Alzheimer’s and Colorectal Cancer
The FDA granted approval for Eli Lilly’s revised dosing regimen of Alzheimer’s drug Kisunla to reduce the risk of brain swelling, addressing safety concerns that had limited its adoption....
ProKidney’s Kidney Disease Cell Therapy Shows Mixed Phase II Results
ProKidney Corp. reported encouraging Phase II trial results for its cell therapy rilparencel in chronic kidney disease patients, showing a 78% slowing of kidney function decline in the two-dose...
AI and Computational Tools Accelerate Cancer Drug Discovery and Protein Engineering
Partnerships and technology developments are advancing AI-driven drug discovery and protein engineering. Revolution Medicines and Iambic Therapeutics formed a multi-year collaboration leveraging...
Biopharma Industry Faces Rising Layoffs and Funding Challenges
Layoffs in the biopharma sector surged 32% year-over-year in the first half of 2025, marking an all-time high for monthly reduction-in-force rounds, with 29 reported in May alone. Several biotechs...