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Precision Oncology Trial Targets Small Cell Lung Cancer Subtypes with Multiomic Biomarker Platform
BostonGene is collaborating with the SWOG Cancer Research Network on the PRISM Phase II trial for extensive-stage small cell lung cancer (ES-SCLC). The study will utilize BostonGene’s machine...
Advances in Targeted Protein Degradation Propel Next-Gen Therapeutics
Targeted protein degradation modalities, including PROTACs and molecular glues, have shown increasing maturity with clinical successes such as Arvinas and Pfizer’s vepdegestrant in breast cancer....
Novartis Gains Ground with First Malaria Drug Approved for Newborns and Infants
Novartis secured regulatory approvals in Switzerland for Coartem Baby, a novel formulation of its malaria combination therapy designed for newborns and infants. This approval addresses an unmet...
Advances in Infant Gut Microbiome Research Highlight Deficiencies Linked to Allergic and Autoimmune Risks
The My Baby Biome study, one of the largest and most diverse investigations into U.S. infant microbiomes, revealed that over 75% of participating babies exhibited key gut bacteria deficiencies...
Samsung Acquires Xealth to Integrate Digital Tools into Clinical Workflows
Samsung announced its acquisition of Xealth, a digital health platform that facilitates the integration of digital health tools into hospital workflows. The move reflects the accelerating demand...
New AI-Powered Platform Enhances Protein Engineering Through Structural and Evolutionary Insights
Researchers developed AiCE, an innovative AI approach that integrates structural and evolutionary constraints into protein engineering models. This method enables accelerated and efficient protein...
AI-Driven Protein Engineering Boosts Research Efficiency
Researchers have developed AiCE, an AI-informed method that integrates structural and evolutionary constraints to accelerate protein engineering. This innovation streamlines the rapid evolution of...
Regulatory Update: FDA Approvals and Industry Challenges
The FDA has recently approved several notable drugs including KalVista Pharmaceuticals' oral treatment for hereditary angioedema, Dizal Pharmaceutical’s sunvozertinib for metastatic non-small-cell...
Cell Therapy Advances and Clinical Developments
Clinical progress continues in cell therapy with promising data from EsoBiotec’s in vivo CAR-T therapy showing responses in multiple myeloma patients, and Australian researchers developing...
Biotech M&A Activity Accelerates Amidst Market Challenges
Concentra Biosciences extended its acquisition spree with a buyout deal for struggling Cargo Therapeutics, following purchases of multiple other biotechs facing operational setbacks. Quanterix...
Malaria Treatment Expanded for Newborns and Infants
Novartis has gained regulatory approval in Switzerland for Coartem Baby, becoming the first to offer a malaria treatment tailored to newborns and young infants. The new formulation includes a dose...
Advances in Precision Oncology and Biomarker-Guided Trials
BostonGene and the SWOG Cancer Research Network are launching a Phase II trial leveraging multiomic platforms to identify molecular subtypes of extensive-stage small cell lung cancer, aiming to...
Emerging Therapeutics Target Immune and Inflammatory Disorders
New treatments show progress against autoimmune and inflammatory conditions. Apogee Therapeutics' anti-IL-13 antibody demonstrated significant efficacy with a more convenient dosing schedule in...
Innovations in Gene Editing and RNA Therapeutics
Breakthroughs in gene editing and RNA-based therapies continue to shape biotech innovation. New software simplifies precision CRISPR genome editing, making it accessible to a broader research...
Biotech Industry Faces Funding Trends and Strategic Shifts
Biopharma financing totaled $28.7 billion in the first half of 2025, marking a 59% decline from the previous year, aligning instead with levels from 2022 and 2023. Med-tech funding, however,...
Microbiome Research Links Infant Gut Deficiency to Disease Risk
The My Baby Biome project, involving 412 infants across the US, found that over 75% of babies exhibit deficiencies in key gut bacteria associated with healthy microbiomes. These deficits correlate...
Novartis launches first malaria drug for newborns after Swiss greenlight
Novartis has secured regulatory approval in Switzerland for Coartem Baby, the first malaria treatment designed for newborns and young infants, addressing a major treatment gap. The company plans...
FDA grants accelerated nod to Dizal's lung cancer therapy ahead of PDUFA
Ahead of its scheduled PDUFA date, the FDA granted accelerated approval to Dizal Pharmaceutical's sunvozertinib (Zegfrovy) for adults with locally advanced or metastatic non-small-cell lung cancer...
Cogent Biosciences advances mastocytosis drug with positive Phase 3 results
Cogent Biosciences announced positive top-line data from its Phase 3 Summit trial evaluating bezuclastinib in non-advanced systemic mastocytosis (SM). The treatment achieved significant...
KalVista’s oral drug wins FDA approval for hereditary angioedema after delay
After a delay attributed to FDA workload constraints, KalVista Pharmaceuticals received FDA approval for Ekterly (sebetralstat), the first oral on-demand treatment for hereditary angioedema (HAE)...