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Concentra Biosciences extends buyout spree with Cargo Therapeutics acquisition
Serial biotech acquirer Concentra Biosciences, led by investor Kevin Tang, finalized a deal to acquire struggling cell therapy company Cargo Therapeutics. Cargo had faced significant challenges...
Single-cell genomics expands rapidly with falling sequencing costs
Single-cell RNA sequencing technology continues to mature, enabling more detailed cellular atlases and multiomic analyses. The International Human Cell Atlas Consortium leads efforts with data...
Apogee Therapeutics reports strong Phase 2 efficacy for IL-13 antibody in eczema
Apogee Therapeutics presented positive Phase 2 results for its anti-IL-13 antibody APG777 in moderate-to-severe atopic dermatitis. The candidate demonstrated a 71% reduction in disease severity by...
AI and biotech converge for protein engineering innovations
Researchers have developed AiCE, an AI-informed strategy that integrates structural and evolutionary constraints for enhanced protein engineering efficiency. This approach accelerates protein...
Biopharma financings see steady activity despite year-over-year decline
Biopharma companies raised $28.74 billion across the first half of 2025, representing a 59% decline compared to the same period in 2024 but aligning with prior years such as 2022 and 2023. Monthly...
Research breakthroughs in RNA, gene therapy and protein degradation emerge
Recent studies showcase advancements across multiple biomedical fields: a Nature Microbiology study identified key amino acid changes enhancing the yellow fever vaccine's safety and efficacy;...
KalVista’s Oral Drug Ekterly Gains FDA Nod for Rare Swelling Disorder
KalVista Pharmaceuticals secured FDA approval for Ekterly, an oral treatment for hereditary angioedema (HAE) attacks in patients aged 12 and above. The drug, sebetralstat, offers a convenient...
Cogent Biosciences Advances Mastocytosis Therapy With Phase 2 and 3 Data
Cogent Biosciences reported positive Phase 2 and Phase 3 clinical trial results for bezuclastinib, a tyrosine kinase inhibitor targeting non-advanced systemic mastocytosis (SM). The drug...
Apogee Therapeutics Shows Promise With Long-Acting IL-13 Antibody in Eczema
Apogee Therapeutics announced compelling Phase 2 data for APG777, its anti-IL-13 antibody targeting atopic dermatitis. The drug significantly reduced disease severity versus placebo and...
BostonGene and SWOG Launch Precision Trial Targeting Small Cell Lung Cancer
BostonGene and the SWOG Cancer Research Network initiated the S2409 PRISM Phase 2 clinical trial for extensive-stage small cell lung cancer (ES-SCLC). Utilizing BostonGene's machine...
Concentra Biosciences Accelerates Biotech Acquisitions With Cargo Therapeutics Buy
Concentra Biosciences, a serial acquirer of struggling biotech firms, has finalized the acquisition of Cargo Therapeutics amid the latter's financial distress and clinical setbacks. The deal...
AI Enables Discovery of Sperm Cells in 'Sterile' Samples, Leading to Pregnancy
Columbia University researchers adapted astrophysics-based AI algorithms to detect sperm cells missed by manual techniques in samples previously deemed sterile. The system, STAR, scanned millions...
Viome Teams With Microsoft to Advance AI-Driven RNA Diagnostics for Preventive Care
Viome Life Sciences partnered with Microsoft to leverage Azure infrastructure for AI-powered RNA-based molecular diagnostics. The collaboration integrates human and microbial gene expression data...
Microbial Carbon Capture via Bacillus megaterium Offers Clean Mineralization Pathway
Researchers from EPFL and partners revealed that the soil bacterium Bacillus megaterium can mineralize CO₂ into high-purity calcium carbonate under elevated CO₂ concentrations, bypassing...
Cytiva Expands Globally With $1.6 Billion in Manufacturing Projects
Cytiva, a Danaher unit specializing in biopharma tools and services, announced completion and growth of $1.6 billion in global expansion initiatives across the U.S., Europe, and Asia. These...
AI Advances Enable Single-Cell Resolution Cell Senescence Tracking
NYU Langone researchers developed a machine learning method analyzing nuclear morphology to identify and monitor senescent cells at single-cell resolution across diverse tissues and aging stages....
KalVista’s Oral HAE Drug Clears FDA After Delay
KalVista Pharmaceuticals received FDA approval for its oral drug Ekterly (sebetralstat), targeting acute swelling attacks in hereditary angioedema (HAE) patients aged 12 and older. This marks the...
Cogent Biosciences’ Bezuclastinib Advances in Mastocytosis
Cogent Biosciences reported positive Phase II/III data for bezuclastinib, a tyrosine kinase inhibitor targeting systemic mastocytosis (SM), a chronic immune disorder. The registrational trial met...
Apogee Therapeutics Advances Atopic Dermatitis Candidate
Apogee Therapeutics unveiled Phase II results for APG777, an anti-IL-13 antibody for moderate-to-severe atopic dermatitis. The treatment demonstrated a 71% reduction in disease severity versus 34%...
Biotech and Regulatory Shifts Impacting Vaccine Policies
Legal challenges have arisen against HHS Secretary Robert F. Kennedy Jr.’s unilateral removal of COVID-19 vaccine recommendations for pregnant women and healthy children. Medical groups, including...