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June 2025 FDA Approvals Highlight Key New Molecular Entities
The U.S. FDA approved 22 drugs in June 2025, tying with March for the highest monthly total this year and contributing to 107 drugs approved in H1 2025. Notable approvals include Gilead’s...
Biopharma Workforce Trends Show Slowing Growth Amid Investment Shifts
The U.S. life sciences job market report indicates a modest contraction with slight hiring declines in 2024 after years of strong growth. During 2023 and 2024, slowdowns in wage increases and a...
Sarepta Restructures Amid Gene Therapy Safety Issues and Market Pressures
Sarepta Therapeutics announced a comprehensive restructuring marked by approximately 500 layoffs (a 36% workforce reduction) as part of a $400 million annual cost-saving initiative. The plan...
10x Genomics and A*STAR Partner on Large-Scale AI-Driven Spatial Omics Study
10x Genomics and Singapore's A*STAR Genome Institute launched the TISHUMAP project, leveraging 10x’s Xenium spatial transcriptomics platform combined with advanced AI to analyze up to 2,500...
Abbott Diagnostics Revenue Dips Amid COVID-19 Test Decline and China VBP Impact
Abbott Laboratories’ second quarter 2025 diagnostics revenue fell 1% year over year to $2.17 billion, pressured by rapid decreases in COVID-19 testing sales and volume-based procurement effects in...
Biotech and Med-Tech Startups Gain Support with Substantial Australian Government Grants
The Australian government awarded nearly AU$100 million (US$64.6 million) in grants to three biopharma and med-tech incubators aimed at fostering emerging startups. These incubators will uplift...
Novartis Names New CFO, Raises Full-Year Sales Guidance
Novartis appointed a new Chief Financial Officer, Mehta, amid ongoing strategic execution and financial management. The Swiss pharmaceutical giant slightly lifted its 2025 full-year sales forecast...
Sarepta gene therapy deaths prompt FDA action and company restructuring
Sarepta Therapeutics is facing significant scrutiny after three patients died following administration of its gene therapies for muscular dystrophies. Two deaths involved Elevidys for Duchenne...
Scipher Medicine pivots to data-driven precision medicine using clinicogenomic datasets
Scipher Medicine is expanding beyond its rheumatoid arthritis molecular diagnostic assay to broader precision medicine efforts in immunology and other non-oncology areas. Under new leadership, the...
FDA advisory committees reject Otsuka's PTSD drug combo and GSK’s Blenrep amid safety concerns
The FDA's advisory committees recently voted negatively on two noteworthy drug candidates. The Psychopharmacologic Drugs Advisory Committee voted 10-1 against Otsuka Pharmaceutical’s combination...
Advancements in biotechnology manufacturing and infrastructure
Significant investments and developments are underway to boost biomanufacturing and life sciences infrastructure globally. GenesisM has commenced construction of a 154,000 square-foot Class A...
Biotechs face funding volatility amid slowing venture capital and public markets
Biotech venture funding slowed significantly in the first half of 2025, with total proceeds dropping to $12.7 billion from $16.9 billion in 2024, underscoring a contraction in capital...
Cutting-edge AI and bioinformatics tools target undruggable proteins and tumor microenvironment
Innovative computational and AI-driven methods are unlocking novel drug discovery pathways. David Baker's lab has engineered AI approaches to design binders targeting intrinsically disordered...
Regulatory and reimbursement challenges impact diagnostic and therapeutic sectors
The FDA and Medicare continue to influence diagnostic test coverage and therapy approvals, shaping market dynamics. Proposed local coverage determinations by Medicare contractor MolDx for...
Notable clinical trial and drug development updates across diverse indications
Recent clinical developments span multiple bioscience areas. Novo Nordisk is preparing Phase 3 trials for an amylin analog and GLP-1 agonist combo targeting weight loss. Diamedica has reported...
Major corporate movements in biotech and med-tech sectors
Strategic leadership changes and corporate consolidations are underway. Novartis named a new CFO, Pranav Mehta, to steer financial strategy amid evolving company goals. Waters Corporation...
Emerging research and technology in neuroscience, immunology, and molecular biology
Cutting-edge studies and innovations shed light on complex biological processes and disease mechanisms. Research explores brain endothelial gap junctions enabling rapid blood flow during neural...
Sarepta’s Gene Therapy Safety Concerns and Major Restructuring
Sarepta Therapeutics faces mounting challenges following the deaths of three patients linked to its gene therapies, notably the Duchenne muscular dystrophy treatment Elevidys and an...
Advances in Three-Person IVF Technology and Mitochondrial Disease Prevention
Recent reports confirm the birth of eight healthy babies in the UK through three-person IVF techniques that replace mitochondrial DNA to prevent transmission of mitochondrial diseases. This...
FDA Advisory Committee Rejects GSK’s Blenrep for Multiple Myeloma
The FDA’s Oncologic Drugs Advisory Committee voted against the approval of GSK’s antibody-drug conjugate Blenrep (belantamab mafodotin) for relapsed/refractory multiple myeloma in combination...