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Scipher Medicine pivots to precision medicine with extensive data partnerships
Scipher Medicine, under new leadership, is transitioning from a diagnostics-only focus toward leveraging its vast non-oncology transcriptomic data for precision medicine development. The firm...
FDA advisory panels reject key drug filings for PTSD and oncology
FDA advisory committees have issued negative votes on notable drug candidates. Otsuka’s combination treatment of Rexulti and Zoloft for PTSD failed to demonstrate convincing efficacy in phase 3...
Bristol Myers’ Reblozyl misses Phase III endpoints in myelofibrosis anemia
Bristol Myers Squibb reported that Reblozyl (luspatercept) failed to meet the primary endpoint in a Phase III INDEPENDENCE trial for treating anemia in myelofibrosis patients, specifically failing...
Xeltis reports positive early clinical results for coronary bypass conduit
Xeltis announced encouraging preliminary safety and patency data from clinical trials evaluating Xabg, its bioengineered coronary artery bypass conduit, in patients with multi-vessel...
AI breakthroughs unlock drug discovery targeting intrinsically disordered proteins
Researchers led by Nobel Laureate David Baker have harnessed artificial intelligence to design protein binders for intrinsically disordered regions (IDRs), previously considered undruggable...
Quantum computing poised to tackle biopharma complexities
Emerging analyses highlight the potential of quantum computing to address complex challenges in biopharma, including molecular modeling and drug discovery processes difficult for classical...
Funding landscape: Seed and Series A investments rise amid concentrated capital
Data from the first half of 2025 indicate an increase in seed and Series A financing rounds within biotech, with $4.7 billion raised. However, the funding landscape is marked by concentration,...
Medical University of Vienna secures €2.5M grant for multiomic biomarker initiative
The Organizational Unit Core Facilities at the Medical University of Vienna received €2.5 million from the Austrian Research Promotion Agency to enhance multiomics-based biomarker discovery and...
GenesisM breaks ground on multi-tenant biomanufacturing hub in Greater Boston
GenesisM, a joint venture between Bain Capital Real Estate and Botanic Properties, has initiated construction on a 154,000-square-foot Class A biomanufacturing facility in Bedford, Massachusetts....
Sarepta Gene Therapy Safety Crisis: Third Death Confirmed
Sarepta Therapeutics is facing escalating safety concerns as a third patient has died after receiving one of its gene therapies. The latest fatality involved a 51-year-old participant in a...
Scipher Medicine Shifts to Data-Driven Precision Medicine Development
Scipher Medicine is evolving its strategy to expand beyond rheumatoid arthritis diagnostics toward broader personalized medicine using clinicogenomic datasets. Under new leadership, Scipher now...
FDA Adcomm Rejects Otsuka’s PTSD Drug Combo: Calls for More Evidence
The FDA Psychopharmacologic Drugs Advisory Committee voted 10-1 against the approval of Otsuka Pharmaceutical's combination therapy of Rexulti and Zoloft for PTSD treatment. Committee members...
Bristol Myers’ Reblozyl Fails Phase III in Myelofibrosis Anemia
Bristol Myers Squibb announced failure of Reblozyl to meet the primary endpoint in the Phase III INDEPENDENCE trial for anemia associated with myelofibrosis, showing no significant reduction in...
GenesisM Breaks Ground on Biomanufacturing Facility in Boston
GenesisM, a joint venture between Bain Capital Real Estate and Botanic Properties, has commenced construction of a 154,000-square-foot Class A biomanufacturing facility in Bedford, Massachusetts....
Thermo Fisher to Acquire Sanofi’s Sterile Manufacturing Site
Thermo Fisher Scientific has agreed to acquire Sanofi’s sterile fill-finish and packaging facility in Ridgefield, New Jersey, enhancing Thermo Fisher’s U.S. manufacturing footprint. The site’s...
AI Advances Undruggable Protein Targeting: Nobel Laureate Baker’s Lab
Researchers from David Baker’s laboratory have developed AI techniques to design protein binders targeting intrinsically disordered regions (IDRs) of proteins, long considered undruggable due to...
Medical University of Vienna Secures €2.5M Grant for Multiomic Biomarker Research
The Medical University of Vienna’s Organizational Unit Core Facilities received €2.5 million from the Austrian Research Promotion Agency to advance multiomics-driven biomarker discovery and...
Funding Trends Show Seed and Series A Up in First Half 2025
Capital flows into early-stage biotech startups have increased in the first half of 2025, with seed and Series A rounds rising to a total of $4.7 billion. However, fewer companies contributed to...
Innovations in Lipid Nanoparticles Enhance mRNA Therapeutic Profiles
A University of Pennsylvania team has demonstrated that modifying the ionizable lipid component of lipid nanoparticles (LNPs) by adding phenol groups can both reduce inflammatory side effects and...
Sarepta gene therapy under FDA scrutiny: third patient death reported
Sarepta Therapeutics is facing intensified regulatory and commercial challenges following the confirmation of a third patient death related to its gene therapy products. The newest fatality...