Get the Daily Brief
Latest Biotech News
Nuclidium and Actithera Secure Major Funding for Radiopharmaceutical Development
European radiopharmaceutical startups Nuclidium and Actithera have completed significant financing rounds to advance their platforms. Nuclidium raised approximately $99 million in Series B funding...
Advances in Diagnostics and Liquid Biopsy Expand Cancer and Disease Monitoring
University of Chicago researchers developed a liquid biopsy method utilizing microbiome-derived cell-free RNA methylation patterns to predict colorectal cancer more accurately than current...
Biopharma IPO, Layoffs, and Investment Landscape Reflect Market Caution
Biopharma financing in Q2 2025 grew modestly to $16 billion, up from Q1 but below historical highs. Despite available capital exceeding $55 billion across numerous venture funds, investment focus...
Merck’s $10 Billion Bet on COPD Drug Verona Pharma
Merck & Co. has agreed to acquire Verona Pharma for $10 billion, a significant move to bolster its respiratory portfolio as it prepares for the patent expiry of its cancer blockbuster Keytruda....
AbbVie Secures $700M Trispecific Antibody for Multiple Myeloma
AbbVie recently inked a licensing agreement with IGI Therapeutics and its subsidiary Ichnos Glenmark Innovation for a trispecific antibody, ISB-2001, targeting multiple myeloma and potentially...
FDA Publishes Complete Response Letters in Transparency Shift
The U.S. Food and Drug Administration (FDA) has for the first time publicly released over 200 complete response letters (CRLs) issued between 2020 and 2024 as part of a transparency initiative....
AI-Designed Protein Targets Antibiotic-Resistant Bacteria
Australian researchers from Monash University and collaborators employed artificial intelligence (AI) to design a novel protein that inhibits heme piracy by pathogenic Escherichia coli, a...
Radiopharmaceuticals Gain Momentum with Major Fundraises
Radiopharmaceutical companies Nuclidium and Actithera have raised significant funds to advance their drug pipelines. Nuclidium completed a $99 million Series B round to support clinical...
Soleno Therapeutics’ Prader-Willi Drug Surpasses Sales Expectations
Soleno Therapeutics reported that its Prader-Willi syndrome drug, Vykat XR, generated estimated net revenues between $31 million and $33 million in Q2 2025, exceeding Wall Street projections....
Chan Zuckerberg Initiative and IGI Fund Pediatric CRISPR Center
The Chan Zuckerberg Initiative (CZI) and the Innovative Genomics Institute (IGI) have jointly funded the Center for Pediatric CRISPR Therapies with a $20 million grant. The Center aims to develop...
New AI Models Capture Complex Gene Networks in Cells
Researchers from Columbia University and the Chan Zuckerberg Initiative have developed GREmLN, a graph-based artificial intelligence model designed to capture complex long-range gene regulatory...
Liquid Biopsy Using Microbial RNA Modifications Predicts Colorectal Cancer
Researchers at the University of Chicago introduced a novel liquid biopsy test employing modification patterns in microbiome-derived cell-free RNA to detect colorectal cancer (CRC) with superior...
Merck Boosts Respiratory Portfolio with $10 Billion Verona Buyout
Merck & Co. has agreed to acquire London-based Verona Pharma for $10 billion, integrating Verona's Ohtuvayre, a first-in-class dual inhibitor of phosphodiesterase 3 and 4 approved for chronic...
AbbVie Invests $700 Million in Trispecific Antibody for Multiple Myeloma
AbbVie announced a $700 million upfront payment to IGI Therapeutics for rights to ISB 2001, a trispecific antibody designed to bind three targets involved in multiple myeloma treatment. The...
FDA Publishes Drug Rejection Letters in Historic Transparency Shift
The U.S. Food and Drug Administration publicly released an initial batch of over 200 complete response letters (CRLs) issued from 2020 to 2024, marking the first time such drug rejection documents...
AI-Driven Collaboration Targets Oncology Drug Discovery
Revolution Medicines and Iambic Therapeutics have formed a multi-year alliance leveraging Iambic’s AI-based drug discovery platforms. The collaboration focuses on applying NeuralPLexer, a...
Soleno Therapeutics’ Rare Disease Drug Sales Outpace Expectations
Soleno Therapeutics reported initial quarterly revenue from its rare disease drug Vykat XR between $31 million and $33 million for the quarter ending June 30, surpassing Wall Street expectations....
Geneoscopy’s Patent Victory Against Exact Sciences in Colorectal Cancer Test
The U.S. Patent Trial and Appeal Board invalidated Exact Sciences’ patent covering a key component of its Cologuard colorectal cancer screening assay following a challenge by Geneoscopy. The PTAB...
Chan Zuckerberg Initiative and Columbia Develop AI Virtual Human Cell Model
Researchers at Columbia University and the Chan Zuckerberg Initiative (CZI) introduced GREmLN, an AI-based virtual human cell model designed to predict cellular state transitions in health and...
Radiopharmaceutical Biotechs Nuclidium and Actithera Secure Major Funding
Two European radiopharmaceutical companies are advancing their clinical and development programs with significant funding rounds. Nuclidium AG raised $99 million in Series B financing to progress...