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Bristol Myers Squibb Names AstraZeneca’s Massacesi as New Chief Medical Officer
Bristol Myers Squibb appointed AstraZeneca executive Cristian Massacesi as its new chief medical officer, succeeding Samit Hirawat. Massacesi, effective August 1, brings a strong track record in...
Leads Biolabs Nears Double Stock Price After $189M Hong Kong IPO
Chinese biotech Leads Biolabs successfully raised approximately $189 million in its Hong Kong stock exchange debut, with shares nearly doubling on the first day. The company plans to use proceeds...
AI Accelerates Immunotherapy Design via T Cell Receptor Cross-Reactivity Prediction
Researchers at Cold Spring Harbor Laboratory developed BATCAVE, a comprehensive database of over 22,000 TCR-peptide interactions, and BATMAN, an AI-driven model that predicts T cell receptor...
Protein Design Breakthrough Challenges Conventional Stability Concepts
A large-scale study led by the Centre for Genomic Regulation and the Wellcome Sanger Institute overturns the notion that protein core mutations universally destabilize structure. Testing thousands...
New AI Designed Protein Binders Target Disease Markers for Immunotherapy
The Baker lab at the University of Washington harnessed AI to design highly specific protein binders for diverse peptide–MHC complexes, enhancing personalized immunotherapy targeting. Detailed in...
European Regulators Approve New Orphan Drugs, Reject Sarepta’s Elevidys
The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted positive opinions for five orphan drugs but rejected Sarepta’s Elevidys gene therapy for Duchenne muscular dystrophy due to...
Deloitte Survey: Life Sciences Face 'Pivotal Moment' Amid Tariffs and Pricing Changes
A global Deloitte survey of healthcare and life sciences executives reveals that tariffs and evolving pricing policies are reshaping strategic planning. Nearly two-thirds expect moderate to major...
Single-Cell Genomics Scaling Revolutionizes Biological Insights
Experts from the Chan Zuckerberg Initiative and Wellcome Sanger Institute highlighted breakthroughs in single-cell RNA sequencing that are transforming biomedical research. Increasing project...
Sarepta’s Elevidys Gene Therapy Faces Regulatory Rejections and Safety Concerns
Sarepta Therapeutics’ Duchenne muscular dystrophy gene therapy, Elevidys, faces mounting regulatory hurdles and safety concerns. The European Medicines Agency’s Committee for Medicinal Products...
Lilly’s Alzheimer’s Drug Kisunla Gains Partial Approval in Europe After Reversal
Eli Lilly’s Alzheimer’s treatment Kisunla (donanemab) experienced a regulatory turnaround by the European Medicines Agency’s CHMP, which changed its previous negative opinion. The CHMP recommended...
Bristol Myers Squibb Names AstraZeneca’s Cristian Massacesi as Chief Medical Officer
Bristol Myers Squibb appointed Cristian Massacesi, formerly chief medical officer at AstraZeneca, as its new CMO effective August 1. Massacesi succeeds Samit Hirawat, who led Bristol Myers’...
Long-Read Sequencing Consortium Expands for 1000 Genomes RNA and DNA Analysis
The 1000 Genomes Project Long-Read Sequencing (1KGP-LRS) Consortium has expanded its scope by incorporating PacBio sequencing in addition to Oxford Nanopore Technologies data. Led by researchers...
AI Advances in Protein and T Cell Receptor Design Accelerate Immunotherapy
Innovations in AI-driven protein design are advancing cancer immunotherapy efforts. Researchers have developed BATMAN, an AI model trained on an extensive database of T cell receptor (TCR) and...
Sustainable Agriculture Innovations Address Climate Challenges and Food Security
Recent studies have highlighted sustainable bio-based farming initiatives and renewable energy integration to enhance food production resilience. European farmers and foresters are leveraging...
Parkinson’s Disease Research Reveals Neural and Immune System Insights
New studies in Parkinson’s disease (PD) are expanding understanding of disease mechanisms and therapeutic approaches. Research highlights glymphatic system asymmetry correlating with symptom onset...
Emerging Leadership and Investment Trends in Biotech and Med-Tech
Biotech and med-tech sectors are witnessing leadership transitions and funding activity amid evolving market conditions. Notable appointments include executives at Thermo Fisher, Agilent, Llusern...
Regulatory Activity and Market Adjustments in Pharmaceutical Sectors
Pharmaceutical and biopharma regulatory landscapes remain dynamic, with key FDA approvals and delays impacting drug availability. The FDA delayed Bayer’s menopause therapy review, while Geneoscopy...
Proteomic and Molecular Biology Advances in Aging and Translation Efficiency
Recent proteomic analyses reveal age-dependent inflection points in human organ aging, notably at around 50 years, with vascular tissues aging most rapidly. Concurrently, studies employing deep...
Sarepta’s Elevidys Gene Therapy Faces Global Regulatory Setbacks
Sarepta Therapeutics’ Duchenne muscular dystrophy gene therapy, Elevidys, confronts increasing regulatory challenges worldwide. The European Medicines Agency’s Committee for Medicinal Products for...
Advances in AI-Driven Immunotherapy and Protein Design
Artificial intelligence is driving significant advances in immunotherapy and protein engineering. The Cold Spring Harbor Laboratory team introduced BATMAN, an AI model predicting T cell receptor...