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Genmab Acquires Merus in $8B Deal to Advance Head and Neck Cancer Bispecific Antibody
Danish biotech Genmab is acquiring Netherland-based Merus for approximately $8 billion in an all-cash transaction, aiming to fully own Merus’ late-stage bispecific antibody petosemtamab, a...
CRISPR’s Evolution: RNA Splitting Mechanism Traced to Type V System Origins
A collaborative team led by Caixia Gao at the Chinese Academy of Sciences revealed the evolutionary origin of Type V CRISPR-Cas systems through the discovery of transposon-CRISPR intermediates...
Advanced AI Differentiates Glioblastoma During Surgery for Real-Time Diagnosis
Harvard Medical School researchers developed an artificial intelligence tool capable of real-time differentiation between glioblastoma and mimicking brain tumors during surgical procedures. This...
UniQure’s Gene Therapy Slows Huntington’s Disease Progression by 75% in 36-Month Data
UniQure reported compelling 36-month clinical data showing its gene therapy candidate AMT-130 significantly slowed Huntington’s disease progression—meeting the primary endpoint with a 75%...
Polymyxin B Antibiotic Kills Bacteria Only When Cells Are Metabolically Active
A University College London-led research team elucidated the mechanism behind polymyxin B’s bactericidal action, revealing it disrupts bacterial outer membranes in an energy-dependent manner....
NeuroKaire Launches Precision Depression Test Using Stem Cell-Derived Neurons
Israeli firm NeuroKaire has commercialized a laboratory-developed test that assesses major depressive disorder through analysis of patient-derived frontal cortical neurons differentiated from...
PHIL Launches Direct-to-Patient Platform to Enhance Access and Affordability in Pharma
PHIL unveiled its direct-to-patient 2.0 platform designed to improve pharmaceutical access and adherence by integrating coverage-first workflows, telemedicine, prescription fulfillment, real-time...
STAT+: FDA’s Top Regulator Criticizes Voclosporin Safety on LinkedIn
George Tidmarsh, the director of FDA’s Center for Drug Evaluation and Research, publicly questioned the safety and clinical benefit of voclosporin, a 2021-approved drug for lupus nephritis, on his...
Long-Term PSA Screening Boosts Early Prostate Cancer Detection and Outcomes
A 12-year cohort study in Korea involving over 5,400 prostate cancer patients demonstrated that sustained prostate-specific antigen (PSA) screening leads to earlier cancer detection and lowers...
Genmab’s $8B Merus Acquisition Fuels Cancer Pipeline Expansion
Danish biopharma Genmab is acquiring Dutch biotech Merus for approximately $8 billion in cash to gain full ownership of Merus’ late-stage cancer assets, including the bispecific antibody...
Advances in AI and Molecular Technologies Enhance Drug Discovery
Cutting-edge AI-driven tools and molecular platforms are transforming drug development and diagnostics. Cadence Molecular Sciences launched ROCS X, an AI-powered molecular screening software...
Breakthroughs in Cancer Therapeutics and Diagnostics
Novel therapeutic candidates and diagnostics advance cancer care. Star Therapeutics secured $125 million to push its monoclonal antibody VGA039 targeting bleeding disorders with potential in von...
Polymyxin B’s Energy-Dependent Mechanism Illuminates Antibiotic Action
New research reveals polymyxin B, a last-resort antibiotic against multidrug-resistant Gram-negative bacteria, kills only metabolically active cells by inducing detrimental outer membrane...
COVID-19 Vaccine Boosters Show Durable Immunity in Long-Term Study
A rigorous 24-month longitudinal study in Indonesia compared the immunogenicity of fractional versus standard dose COVID-19 vaccine boosters in healthy adults. Published in Nature Communications,...
Innovations in Radiation Therapy Match Surgery Outcomes in Lung Cancer
A landmark decade-long clinical trial has established that stereotactic radiation therapy delivers survival outcomes on par with surgical resection in early-stage non-small cell lung cancer...
New mRNA Vaccine Shows Promise in Treating Macular Degeneration
Japanese researchers developed an mRNA vaccine that suppresses pathological retinal neovascularization underlying age-related macular degeneration in mouse models. This intramuscular vaccine...
Direct-to-Patient Platforms Respond to Drug Pricing Pressures
With US drug pricing reforms looming, pharmaceutical firms have introduced direct-to-patient models to enhance medication accessibility and affordability. PHIL launched its Direct-to-Patient 2.0...
FDA Leadership Change and Regulatory Policy Shifts in Drug Approval
Dr. Anthony Letai, a renowned oncologist and cell death pathway expert, has been appointed director of the National Cancer Institute, promising a renewed focus on biomarker discovery and...
Exercise and Immune Recovery in Post-COVID Syndrome
A randomized controlled trial presented at the European Respiratory Society Congress demonstrated that structured exercise significantly recalibrates immune function in individuals with post-COVID...
Genmab's $8B Merus Acquisition Transforms Head and Neck Cancer Pipeline
Genmab has finalized an $8 billion all-cash acquisition of Dutch biotech Merus, securing rights to its phase III-stage bispecific antibody, petosemtamab, targeting head and neck cancer....