Latest Biotech News

Erasca shares plunged 53% after a disclosed patient death related to a grade 3 pneumonitis event in an ERAS-0015-treated individual. The company described the event in footnotes as a rare toxicity...

Researchers published in Science a synthetic-biology approach to create an organism that uses fewer amino acids, partially removing isoleucine from key protein sequences in the ribosome. Using...

A study published on CD44+ monocytes identifies a mechanistic driver of inflammation in bronchopulmonary dysplasia (BPD) among very premature infants. By focusing on monocyte subsets bearing CD44,...

Researchers reported that cGAS–STING hyperactivation drives liver inflammation in Down syndrome, providing a mechanistic explanation for hepatic vulnerability in the condition. The study...

Nature Communications reports a magnesium-implant coating strategy designed to actively change wettability to support osteoporotic fracture healing. Researchers engineered an...

Researchers unveiled an integrated biopsy approach combining shock-scattering micro-histotripsy with fine needle aspiration to improve sample quality for downstream pathology and biomarker...

A study in the Journal of Exposure Science and Environmental Epidemiology describes a capillary blood collection device to track veterans’ PFAS exposure. The approach uses a less cumbersome...

A proposed measure would ban the use or consideration of China clinical trial data, reflecting renewed congressional concerns in Washington about data access, credibility, and competitive dynamics...

The FDA approved Arvinas’ PROTAC breast cancer therapy Veppanu (formerly vepdegestrant) for ESR1-mutated, metastatic estrogen receptor-positive, HER2-negative breast cancer after at least one...

Rigel Pharmaceuticals published final additional follow-up data from the Phase 1/2 ARROW trial of pralsetinib (GAVRETO) in metastatic RET fusion-positive non-small cell lung cancer in the Journal...

The FDA has twice declined to approve Replimune Group’s oncolytic immunotherapy RP1 for melanoma, despite the program receiving breakthrough therapy designation and fast-track attention. Reporting...

Researchers at UC San Diego reported in Cell that restoring impaired protein recycling can reverse T-cell exhaustion in mouse models. The work, led by Ananda Goldrath’s lab, links proteostasis...

Weill Cornell Medicine researchers reported in Cancer Cell that activated T cells can secrete extracellular vesicles containing DNA that enter immune and tumor cells to enhance antigen processing...

Four biotech initial public offerings raised about $1.5 billion in April, the largest month for IPO proceeds in more than five years, according to Renaissance Capital. The new flotations included...

A proposed policy move would ban or limit China clinical trial data in a way that reflects increased congressional concern about competition from China, according to reporting. The measure signals...

Cytiva and Rockwell Automation launched Figurate SCADA, a supervisory control and data acquisition system aimed at reducing digital bottlenecks in biopharmaceutical manufacturing. The platform is...

Infinite Epigenetics acquired Tally Health, expanding its platform to cover epigenetic diagnostics, adult DNA methylation datasets, and personalized interventions focused on improving healthspan....

Guardant Health, Delfi Diagnostics, and Singular Genomics reported leadership changes across oncology liquid biopsy and genomics platforms. Guardant said Craig Eagle, chief medical officer, will...

The FDA approved Pfizer and Arvinas’ protein-degrading breast cancer drug Veppanu (formerly vepdegestrant) for patients with metastatic, estrogen receptor-positive, HER2-negative breast cancer...

Rigel Pharmaceuticals published final Phase 1/2 ARROW study data in the Journal of Clinical Oncology for pralsetinib (Gavreto) in metastatic RET fusion-positive NSCLC, adding 42 months of...