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US Expands Export Control Entity List to Include Three Chinese Biotech Firms
The US Department of Commerce's Bureau of Industry and Security added 32 new entities to its Entity List, notably including three Chinese biotechnology companies: Beijing Tianyi Huiyuan...
Deep Learning Model Advances Lung Nodule Cancer Risk Assessment
A novel artificial intelligence-based deep learning algorithm has demonstrated superior accuracy in stratifying malignancy risk of lung nodules, according to recent findings published in...
Microglial Diversity and Clonal Expansion Characterized After Ischemic Stroke
Researchers using multicolor fate mapping techniques in mouse models have elucidated the intricate polyclonal proliferation and heterogeneity of microglia following ischemic stroke. The study...
Stem Cell Transplantation Promotes Brain Regeneration After Stroke in Mice
A recent study demonstrated that stem cell transplantation enhances brain cell regeneration and improves functional recovery following ischemic stroke in mouse models. The findings underscore the...
STAT+: Areteia Therapeutics’ Phase 3 Asthma Drug Dexpramipexole Shows Lung Function Improvement
Privately held Areteia Therapeutics announced that dexpramipexole, an oral twice-daily drug candidate, met its primary endpoint by improving lung function in a placebo-controlled Phase 3 study...
Lila Sciences Raises $235 Million Series A to Advance AI-Driven Drug Discovery
Flagship Pioneering-backed startup Lila Sciences secured $235 million in Series A funding to develop 'scientific superintelligence' by integrating artificial intelligence into laboratory research...
Novartis Secures $120 Million Upfront in Second Monte Rosa Molecular Glue Deal
Novartis has expanded its partnership with Monte Rosa Therapeutics by acquiring exclusive rights to a new molecular glue degrader candidate for immune diseases, along with options for two...
ATyr Pharma’s Efzofitimod Fails Phase 3 Pulmonary Sarcoidosis Trial, Shares Drop Over 80%
Biotech company ATyr Pharma announced that its lead drug candidate, efzofitimod, did not meet the primary endpoint in a Phase 3 trial for pulmonary sarcoidosis, an inflammatory lung disease. The...
Novo Nordisk Announces 9,000 Job Cuts Amidst Intensifying Glp-1 Competition
Novo Nordisk disclosed plans to reduce its global workforce by 11.5%, equating to approximately 9,000 layoffs, as part of a company restructuring aimed at enhancing commercial execution in...
AI Toolkit Integrates Multi-Omics Data to Advance Precision Oncology
Researchers at the Berlin Institute for Medical Systems Biology have developed Flexynesis, a deep learning framework designed to integrate diverse multi-omics datasets, including genomic,...
GHO Capital Acquires Scientist.com to Expand Drug Development Marketplace
Private equity firm GHO Capital has completed the acquisition of Scientist.com, a pioneering online marketplace that connects pharmaceutical companies with contract research organizations (CROs)...
Cleveland Clinic Findings Favor Bariatric Surgery Over GLP-1 Medications for Long-Term Obesity Management
A large observational study published in Nature Medicine by Cleveland Clinic researchers demonstrates that bariatric surgery delivers more substantial and sustained health benefits than GLP-1...
CatalYm Reshapes Leadership to Accelerate Immuno-Oncology Candidate Development
Immunotherapy biotech CatalYm has appointed four seasoned industry executives, including Sujata Rao as Chief Medical Officer and Clinton Musil as Chief Business and Financial Officer, while three...
Biopharma CDMO Sector Forecast to Surge with Biologics Demand Leading Growth
A Jefferies report highlights robust growth prospects for contract development and manufacturing organizations (CDMOs), projecting the market to expand from $173 billion in 2024 to $323 billion by...
Breakthrough Single-Cell RNA Study Maps Plant Stem Cell Regulators with Crop Yields Implications
Cold Spring Harbor Laboratory scientists have generated a comprehensive gene expression atlas revealing rare stem cell regulators in maize and Arabidopsis via single-cell RNA sequencing. This...
University of Cambridge Unveils Cancer Immunotherapy via STING Pathway Activation
Researchers at the University of Cambridge have developed a novel immunotherapeutic approach that activates the STING pathway, an innate immune sensor, to enhance immune defenses against cancer....
Novartis Expands Molecular Glue Collaborations – $5.7 Billion Deal with Monte Rosa
Novartis has secured a $120 million upfront deal with Boston-based Monte Rosa Therapeutics to develop molecular glue degraders targeting immune-mediated diseases, with potential payments up to...
aTyr Pharma’s Efzofitimod Fails Phase III Trial in Pulmonary Sarcoidosis – Shares Drop 80%
Biotech company aTyr Pharma announced that its experimental drug efzofitimod failed to meet the primary endpoint in a Phase III trial for pulmonary sarcoidosis, an inflammatory lung disease. The...
US Health and Human Services Cuts $500M from mRNA Vaccine Research Funding
US HHS Secretary Robert F. Kennedy Jr. has canceled $500 million in funding for 22 mRNA vaccine projects, citing concerns over efficacy and safety, redirecting funds towards whole-virus vaccine...
Novo Nordisk Plans 9,000 Layoffs Amid Rising Competition in Diabetes and Obesity Market
Novo Nordisk announced plans to cut approximately 9,000 jobs, about 11.5% of its workforce, aiming to streamline management and improve commercial execution. The company faces intense competition...