Get the Daily Brief
Latest Biotech News
Breakthrough in Programmable Chromosome Engineering Enables Megabase-Scale Genome Editing
Chinese researchers led by Professor Gao Caixia developed programmable chromosome engineering (PCE) systems achieving precision editing at megabase scale in eukaryotic cells. Their innovations...
FDA Cancer Regulator Stops Replimmune's Melanoma Drug Amid Internal Disputes
The FDA's Oncology Center of Excellence director, Richard Pazdur, intervened late in the review of Replimmune's melanoma therapy RP1, contributing to its rejection despite earlier support within...
Twist Bioscience Reports Record Q3 Revenues, Narrows 2025 Guidance
Twist Bioscience posted an 18 percent year-over-year revenue increase in Q3 2025, driven by growth in next-generation sequencing and synthetic biology sectors. Despite this, the company slightly...
Vertex Pharmaceuticals Faces Setbacks in Pain Drug Development
Vertex Pharmaceuticals reported a Phase 2 failure for its next-generation non-opioid pain candidate VX-993, which did not outperform placebo in bunionectomy pain, leading the company to...
Sophia Genetics Expands Collaboration with AstraZeneca, Reports 16% Revenue Growth
Sophia Genetics reported a 16 percent year-over-year revenue increase for Q2 2025, fueled by robust molecular analyses on its AI-driven platform. The company announced an expanded multi-year...
Emerging Therapies and Advances in Cancer Immunotherapy and Oncology
Significant advancements in oncology include: UNC Lineberger’s symposium highlighting progress in cancer research; novel dual-target therapies aiming at colorectal and breast cancers; innovative...
Microplastics and Nanoplastics: Environmental and Human Health Insights
Recent studies reveal micro- and nanoplastics' pervasive presence across ecosystems and human tissues, with advances in detection technologies such as AI and Raman spectroscopy improving...
Glucagon-Like Peptide-1 (GLP-1) Drugs: Clinical Effects and Coverage Developments
New research suggests that GLP-1 receptor agonists like semaglutide may reduce muscle strength in mice despite stable muscle size, raising questions for older populations. Policy shifts in the US...
Biotech Industry Funding, Partnerships, and Workforce Challenges
The life sciences sector faces a mixed landscape, with major funding rounds closing as OrbiMed raises $1.86 billion for its fifth fund and Abbivax, MapLight, Everest Medicines secure significant...
Innovations in Energy Storage and Battery Technology
Researchers report groundbreaking advancements in battery materials, including the development of novel sodium-ion cathodes via combustion synthesis and enhanced lithium-ion cathodes through...
Groundbreaking Genomic and Protein Engineering Technologies
Chinese scientists achieved megabase-scale precise genome editing in eukaryotic cells using programmable chromosome engineering platforms, overcoming limitations of Cre-Lox systems through...
Tariffs Hit Pharma Imports as Trump Signals Up to 250% Levies
The U.S. administration under former President Donald Trump has announced plans to impose escalating tariffs on pharmaceutical imports, starting with a small duty and potentially rising to 250%...
Precision Genome Editing Scales to Megabase Ranges in Eukaryotes
Chinese researchers have pioneered novel genome editing platforms termed Programmable Chromosome Engineering (PCE), achieving unprecedented megabase-scale DNA manipulations in eukaryotic cells. By...
Vertex Pharmaceuticals Faces Setbacks on Pain Drug Development
Vertex Pharmaceuticals announced the failure of a next-generation non-opioid pain candidate, VX-993, in a Phase 2 trial for acute pain following bunionectomy, resulting in termination of pivotal...
Microplastics Found in Human Blood and Environment: New Analytical Advances
Emerging studies highlight the pervasive infiltration of micro- and nanoplastics in human biological systems and the environment, prompting concerns over health implications. Researchers employ...
Repligen Partners with Novasign to Boost Bioprocessing Digitalization
Repligen announced a strategic partnership with Novasign to integrate advanced machine learning and modeling workflows into its filtration systems, enhancing digitalization and process analytical...
Glioblastoma Research Gains Momentum Through New Trials and Investments
After years of limited progress in glioblastoma treatment due to high clinical failure rates and industry retreat, renewed interest and funding are driving advancements in therapeutics and trial...
AI Advances in Protein Engineering Target Intrinsically Disordered Proteins
Researchers led by Nobel laureate David Baker have harnessed deep learning methods to design peptides capable of binding intrinsically disordered proteins (IDPs), which traditionally have been...
Clinical and Molecular Insights in Cancer, Immunotherapy, and Precision Medicine
A suite of recent studies spanning oncology reveal novel biomarkers, immunotherapeutic targets, and precision medicine tools. Highlights include the identification of Ephrin B3 in cutaneous...
Sophia Genetics Expands AI Collaboration with AstraZeneca Amid Revenue Growth
Sophia Genetics reported a 16% year-over-year revenue increase to $18.3 million for Q2 2025, driven by growth outside biopharma sectors. The company expanded its multimodal AI collaboration with...