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Latest Biotech News

New immunotherapy strategy targets thyroid cancer with dual checkpoint inhibition

April 05, 2026

A phase II GETNE-DUTHY trial evaluating durvalumab plus tremelimumab reported findings in advanced thyroid carcinoma, aiming to expand immunotherapy options for a cancer type with limited...

Mechanistic cancer immunology points to glycocholic acid as a checkpoint-efficiency modifier

April 05, 2026

Researchers reported that circulating glycocholic acid (GCA) can modulate the efficacy of colorectal cancer immune checkpoint therapy. The findings, described in a study focused on tumor...

Checkpoint-adjacent immuno-oncology and targeted therapy mapping in SCLC

April 05, 2026

New research reported molecular profiling work designed to guide targeted and immunotherapy selection in small cell lung cancer (SCLC), a disease marked by rapid progression and heterogeneous...

Gene-therapy and epigenetics: KDM4 inhibition reactivates a tumor suppressor in AML models

April 05, 2026

Researchers from The Jackson Laboratory (JAX) reported an epigenetic strategy that reactivates the tumor suppressor ZBTB7A in acute myeloid leukemia (AML) models. In a mouse study published in...

Dealmaking and management moves: Curve Therapeutics adds a CMO for liver expertise

April 05, 2026

Curve Therapeutics, a University of Southampton spinout focused on transcription factors and other intracellular targets, appointed liver specialist Amit Singal to join its leadership as...

Biotech finance: Ambrosia and Syneron pursue nine-digit Series B funding rounds

April 05, 2026

Finance coverage highlighted that Ambrosia and Syneron are moving toward the clinic with nine-digit Series B rounds, according to the sourced financing report. The recap places the deals...

Health platform integration: Abbott tests move into Flatiron’s OncoEMR workflow

April 05, 2026

Abbott partnered with Flatiron Health to integrate Abbott’s precision oncology testing menu into Flatiron’s cloud-based electronic medical record platform, OncoEMR. The integration enables...

Pervasive policy pressure: Trump revives pharma tariffs with 100% charges but leaves drug loopholes

April 05, 2026

The Trump administration revived a pharma tariff framework with 100% charges under “Section 232,” while analysts cited exemptions and loopholes that would limit coverage across a wide set of...

FDA approval and gene-therapy milestone

April 05, 2026

Rocket Pharmaceuticals said the FDA approved its gene therapy Kresladi (marnetegragene autotemcel) for leukocyte adhesion deficiency type I, and the program earned a rare pediatric disease...

Biopharma data platforms and discovery collaboration

April 05, 2026

TriNetX will link its large de-identified health database with Regeneron for genomic and proteomic data access under an exclusive, secure, licensed arrangement covering roughly 300 million...

Clinical genomics and multi-omics instrumentation rollout

April 05, 2026

Caris Life Sciences launched Caris ChromoSeq, a combined whole-genome sequencing and whole-transcriptome assay aimed at improving clinical genomic evaluation for myeloid malignancies. The test...

MCED oncology diagnostics trial scrutiny

April 05, 2026

Clinicians offering early access to Grail’s multi-cancer early detection (MCED) test are waiting for a full NHS trial readout after an endpoint miss, according to reporting. The situation is...

Oncology supportive care: EGFR-mutant NSCLC skin toxicity reduction

April 05, 2026

Interim results from the phase II COCOON trial showed a 50% reduction in dermatologic toxicities when proactive skincare was used in frontline EGFR-mutant non-small cell lung cancer patients. The...

Epigenetic reactivation strategy in acute myeloid leukemia

April 05, 2026

Researchers at The Jackson Laboratory (JAX) reported an epigenetic approach that reactivates a tumor suppressor gene in acute myeloid leukemia models. In mouse experiments published in Science...

Hematology: post-ibrutinib transplant outcomes and risks

April 05, 2026

A new analysis examines clinical outcomes and risks following transplantation in patients with relapsed or refractory mantle cell lymphoma after ibrutinib exposure. The focus is on how targeted...

Obesity–immunology link in type 2 diabetes

April 05, 2026

Researchers reported evidence connecting obesity with functional exhaustion of circulating γδ T cells in individuals with type 2 diabetes, tying metabolic disease severity to changes in an...

Regenerative/investigational delivery: hemostatic microgels for neonatal surgery

April 05, 2026

Biomedical engineers from the University of North Carolina at Chapel Hill and North Carolina State University reported development of an injectable hemostatic microgel to reduce bleeding in...

Business and policy: EU biotech competitiveness effort

April 05, 2026

Industry stakeholders discussed the proposed EU Biotech Act as a lever to improve European biotech competitiveness, with emphasis on manufacturing supply chains and harmonized pathways to market....

FDA gene therapy approval and pediatric priority review voucher

April 05, 2026

FDA approved Rocket Pharmaceuticals’ gene therapy Kresladi (marnetegragene autotemcel) for leukocyte adhesion deficiency type I, the company said, making it one of the March approvals that earned...

Data partnership for large-scale genomic and proteomic access

April 05, 2026

TriNetX and Regeneron announced an agreement linking genomic and proteomic data for drug discovery and development, with TriNetX providing Regeneron exclusive, secure access to de-identified...