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IU chemists discover chemical approach to combat antibiotic resistance
Researchers at Indiana University reported a chemical strategy that restores antibiotic activity against resistant bacteria, presenting a potential adjunct to existing antibiotics. The study...
Brown study reveals pathway to boost glioblastoma therapy response
Scientists at Brown University identified a molecular mechanism that modulates glioblastoma treatment sensitivity and proposed strategies to enhance therapeutic efficacy in preclinical models. The...
Lentiviral vectors retool gene therapy delivery — new techniques reported
A recent study reviewed advances in lentiviral vectors that expand utility for viral gene‑therapy applications, highlighting improvements in tropism, safety, and manufacturing. The research...
Scientists program microbes to synthesize compounds with light
Researchers at the Carl R. Woese Institute for Genomic Biology demonstrated enzymatic transformations inside living microbes that are driven by light, enabling new biosynthetic routes to valuable...
AI system diagnoses sarcopenia accurately — new decision support tool
Developers unveiled the Sarcopenia Artificial Intelligence Diagnostic Decision Support System (SAID DSS), an AI model that identifies sarcopenia with high accuracy using clinical and imaging...
Machine learning exposes scope of paper‑mill fraud in cancer research
A Queensland research team developed a machine‑learning tool that mapped the prevalence and networks of fraudulent papers—so‑called paper mills—affecting the cancer literature. The model...
AstraZeneca doubles down on obesity — $1.2B up front in CSPC China pact
AstraZeneca signed a landmark partnership with China’s CSPC that delivers $1.2 billion up front and grants the U.K. pharma access to eight obesity assets, including a once‑monthly GLP‑1/GIP...
Intranasal H5N1 vaccine prevents infection in rodents: WashU study
Researchers at Washington University in St. Louis reported an intranasal adenoviral‑vectored H5N1 vaccine that produced robust mucosal and systemic immunity and prevented H5N1 infection in mice...
FDA halts two Regenxbio gene‑therapy trials — cancer case raises approval doubts
Regulatory scrutiny intensified after the FDA placed tests of two Regenxbio gene‑therapy programs on clinical hold following a patient’s cancer diagnosis in one study, according to MedCity News....
Cardiff’s CEO exit rattles investors — shares plunge despite Phase II news
Cardiff Oncology reported positive Phase II data for onvansertib in RAS‑mutated metastatic colorectal cancer but the company simultaneously announced the resignations of CEO Mark Erlander and CFO...
CZI lays off 70 staff — overhauls for AI‑powered biology push
The Chan Zuckerberg Initiative announced cuts of about 70 employees as it reorients toward AI‑driven biomedical research and consolidates prior research entities into a unified science...
Thermo Fisher to close Massachusetts site — 100+ layoffs at Franklin facility
Thermo Fisher Scientific filed notice of a facility closure at 27 Forge Parkway in Franklin, Massachusetts, and plans layoffs affecting more than 100 employees, according to reporting on the...
Lentiviral vectors redefine gene delivery — study maps new therapeutic techniques
A new review highlights lentiviral vectors’ expanding role in gene‑therapy design, describing engineered constructs and delivery advances that improve transduction efficiency, tropism, and safety...
Machine‑learning tool uncovers paper‑mill fraud in cancer literature — reproducibility alarm
Researchers at Queensland developed a machine‑learning tool that identifies signs of paper‑mill–generated manuscripts and applied it to the cancer literature, uncovering a wide spread of likely...
MD Anderson picks Iakovos Toumazis to lead oncology data science — prevention focus
The Institute for Data Science in Oncology at MD Anderson appointed Iakovos Toumazis, Ph.D., to lead its work on data science innovations in cancer prevention and decision support. Toumazis brings...
Black‑market GLP‑1 trade booms — peptides shipped from China amid shortages
Investigative reporting described a thriving gray‑market trade in GLP‑1–class peptides and other fitness‑oriented peptides sourced from Chinese manufacturers and sold to Western consumers at steep...
Nasal H5N1 vaccine halts infection in rodents — WashU study
Washington University researchers reported an intranasal adenoviral‑vectored H5N1 vaccine that prevented infection in mice and hamsters in preclinical tests. Published in Cell Reports Medicine,...
Gene therapy regulatory shock: Regenxbio trials held; Ultragenyx resubmits
Regulatory scrutiny tightened around AAV gene therapies this week as the FDA placed two Regenxbio studies on clinical hold after a patient in one trial developed cancer, and Ultragenyx formally...
AstraZeneca pays $1.2B up front for CSPC obesity and diabetes assets
AstraZeneca struck a major China‑focused deal with CSPC Pharmaceutical Group that includes an up‑front payment of $1.2 billion and rights to multiple metabolic assets, among them a once‑monthly...
Beckman Coulter and Automata link instruments to AI‑ready automation
Beckman Coulter Life Sciences and Automata announced a strategic partnership to integrate Beckman liquid‑handling, genomic and cell analysis systems into Automata’s LINQ automation ecosystem. The...