Latest Biotech News

UCB has committed $2 billion toward expanding Candid’s T-cell engager platform, signaling a major push into engineered cell-engaging therapies for autoimmune disease. The investment underscores...

Rigel Pharmaceuticals published final results from the Phase 1/2 ARROW study of pralsetinib (Gavreto) for RET fusion-positive metastatic NSCLC in the Journal of Clinical Oncology, adding 42 months...

The FDA has twice opted not to approve Replimune’s oncolytic immunotherapy RP1 for melanoma despite breakthrough therapy designation and fast-track expectations, according to the account provided....

Erasca’s shares fell sharply after the company disclosed a fatal adverse event connected to ERAS-0015, its oral pan-RAS molecular glue in early trials. The disclosure accompanied preliminary...

Researchers have identified CD44+ monocytes as key drivers of inflammation in bronchopulmonary dysplasia (BPD) in very premature infants, tying a specific immune cell phenotype to the...

A new method combining shock-scattering micro-histotripsy with fine needle aspiration (FNA) aims to improve how much cellular material is retrieved for downstream biomarker profiling and...

Scientists report progress toward organisms with fewer amino-acid building blocks by partially eliminating isoleucine usage in Escherichia coli ribosome proteins, with the research published in...

A study identifies cGAS–STING hyperactivation as a mechanism that may help explain the elevated risk of liver inflammation seen in individuals with Down syndrome. By linking innate immune sensing...

A study in the British Journal of Cancer assesses the cost-effectiveness of integrating AI into the UK breast cancer screening program alongside traditional mammography. The analysis evaluates the...

Researchers report that African swine fever virus (ASFV) uses an MGF505-1R protein to degrade the host factor p300, helping the virus manipulate cellular machinery to support replication and...

The FDA rejected RP1, an engineered oncolytic herpesvirus therapy by Replimune Group, despite earlier “breakthrough therapy” designation tied to promising melanoma trial results. The agency has...

Biotech capital markets remain active, with April bringing the biggest month for IPO proceeds in more than five years. Four new biotech companies priced upsized offerings, raising $1.5 billion,...

Erasca shares plunged 53% after a disclosed patient death related to a grade 3 pneumonitis event in an ERAS-0015-treated individual. The company described the event in footnotes as a rare toxicity...

Researchers published in Science a synthetic-biology approach to create an organism that uses fewer amino acids, partially removing isoleucine from key protein sequences in the ribosome. Using...

A study published on CD44+ monocytes identifies a mechanistic driver of inflammation in bronchopulmonary dysplasia (BPD) among very premature infants. By focusing on monocyte subsets bearing CD44,...

Researchers reported that cGAS–STING hyperactivation drives liver inflammation in Down syndrome, providing a mechanistic explanation for hepatic vulnerability in the condition. The study...

Nature Communications reports a magnesium-implant coating strategy designed to actively change wettability to support osteoporotic fracture healing. Researchers engineered an...

Researchers unveiled an integrated biopsy approach combining shock-scattering micro-histotripsy with fine needle aspiration to improve sample quality for downstream pathology and biomarker...

A study in the Journal of Exposure Science and Environmental Epidemiology describes a capillary blood collection device to track veterans’ PFAS exposure. The approach uses a less cumbersome...

A proposed measure would ban the use or consideration of China clinical trial data, reflecting renewed congressional concerns in Washington about data access, credibility, and competitive dynamics...