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Platform launch: spatial transcriptomics moves toward whole-transcriptome scaling
10x Genomics unveiled its Atera spatial platform at AACR 2026, pitching whole-transcriptome spatial biology at higher throughput and plex than its prior Xenium system. The company said Atera...
Gene editing: base editing corrects cardiac Fabry mutation in cells
Researchers reported that adenine base editing (ABE) can rescue a cryptic splice mutation tied to cardiac-type Fabry disease in cells. The work, published in Gene Therapy, targets a specific G>A...
Precision immunotherapy competition: emerging KRAS inhibitor race
STAT+ highlighted how the search for durable KRAS-mutant therapies has accelerated since early KRAS drugs fell short on response durability. The report centers on Revolution Medicines’...
Clinical surveillance: wastewater finds drug-resistant Candida auris signals
A Nature Communications study reported that wastewater-based epidemiology can detect the emergence of clinically significant, drug-resistant Candida auris in healthcare settings. Researchers used...
Company leadership and funding: new hires and board changes across biotech
Grey Wolf Therapeutics appointed serial entrepreneur Edwin Moses as chair, while Harbour BioMed (HBM Holdings) hired Adam Zong as president. Moses’ background includes leadership roles across UK...
Regulatory policy: FDA budget priorities shape pediatric voucher strategy
A BIOCENTURY report said the FDA’s budget proposal includes a policy wish list that would make pediatric priority review vouchers permanent and would reduce industry participation on advisory...
Cell and drug safety: peptide compounding under FDA scrutiny
CSPI criticized the FDA’s plans to convene a Pharmacy Compounding Advisory Committee meeting in July to consider adding seven injectable peptides to what can be compounded. The statement argues...
Research funding and talent: NSF graduate fellowship awards rebound
The NSF awarded a record 2,599 Graduate Research Fellowships after previously cutting the number to 1,000 the year before. The rebound, announced after concerns that application timing and...
Pancreatic cancer efficacy signal in Phase 3
Revolution Medicines said its Phase 3 study of daraxonrasib in advanced pancreatic adenocarcinoma produced a median survival of 13.2 months versus 6.7 months with standard chemotherapy, delivering...
Biotech financing and IPOs
Kailera Therapeutics’ upsized IPO raised $625 million to fund global clinical trials across its pipeline of injectable and oral obesity drug candidates, extending investor focus on anti-obesity...
Gene therapy research recognition
The Breakthrough Prize Foundation awarded Life Sciences prizes to pioneering teams behind landmark gene therapies, including work connected to a US-available retinal blindness treatment and...
Base editing for cardiac Fabry disease
Researchers reported an adenine base editing approach that corrects a cryptic splice mutation (IVS4+919, G>A) underlying cardiac-type Fabry disease in cells, according to a study published in Gene...
Antibacterial and antifungal surveillance via wastewater
A Nature Communications study used wastewater-based epidemiology to detect the emergence of clinically significant and drug-resistant Candida auris strains in healthcare settings, mapping how...
FDA policy and enforcement direction
Two separate policy updates pointed to a more enforcement-led FDA posture affecting both review and promotion of therapeutics. One report described an FDA budget proposal including policy “wish...
Immunology platform: targeted lung cytokine gene delivery
Scientists reported an AAV6.2 gene delivery system designed to drive localized expression of immunomodulatory cytokines in mouse lungs during inflammatory challenges, without detectable peripheral...
Regulatory and commercial expansion in spatial genomics
10x Genomics launched its Atera spatial platform at AACR 2026, positioning it as whole-transcriptome spatial biology at scale intended to reduce trade-offs seen in existing spatial tools. In...
Seizure cell therapy deal for UCB
UCB agreed to buy Neurona for up to $1.2 billion, aiming to add a potentially one-off seizure cell therapy to its primarily small-molecule portfolio. The transaction is intended to diversify...
Corporate hiring and leadership moves in life science tooling
Bruker announced leadership transitions within its BioSpin organization, with Falko Busse set to transition out of executive officer and BioSpin Group president roles around May 1, 2026. Jackson...
Pancreatic cancer – next-gen KRAS targeting
Revolution Medicines’ daraxonrasib, a KRAS-focused oral therapy, delivered a survival benefit in a Phase 3 pancreatic cancer readout highlighted by STAT+. In advanced pancreatic adenocarcinoma,...
Regulatory strategy – Roche seeks EMA path for Duchenne gene therapy
Roche is laying additional groundwork for European regulators on its Duchenne muscular dystrophy gene therapy Elevidys (delandistrogene moxeparvovec). The company announced a further global Phase...