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Wildfire Smoke Tied to Elevated Cardiovascular Risks in California
A study analyzing Northern California's 2018 wildfires revealed significant increases in cardiovascular hospitalizations and mortality during dense smoke exposure from the Mendocino Complex fire....
Marathon Running Temporarily Alters Brain Myelin Structure
University of the Basque Country neuroscientists documented that marathon runners experience short-term reductions in brain myelin content, especially in white matter tracts critical for...
Genetic Diversity Influences Tumor Immunotherapy Outcomes in Mice
Researchers at The Jackson Laboratory employed genetically diverse Collaborative Cross mice to dissect how inherited variability affects tumor response to immune checkpoint inhibitors. Their...
FDA Publishes Drug Rejection Letters Amid Transparency Push
The FDA released over 200 complete response letters as part of efforts to increase transparency in its drug review process. However, the agency imposed limitations on the scope of disclosures....
Rutgers Study Links Synaptic Protein Modification to Brain Plasticity
A Rutgers-led team identified the protein cypin as a regulator of K63-linked polyubiquitination, modulating synaptic protein composition in mice. This post-translational modification influences...
Identification of Extensive Misfolded Proteins in Aging Brain
Johns Hopkins researchers used limited proteolysis mass spectrometry to detect over 200 misfolded proteins potentially linked to age-related cognitive decline in rats. This expands the scope...
Repligen-Univercells Alliance Brings Real-Time Viral Vector Monitoring
Univercells Technologies partnered with Repligen to integrate MAVEN® Real Time Glucose Control within scale-X bioreactors, enabling continuous, nondestructive monitoring of glucose and lactate...
Fecal Microbiota Transplants Expand Beyond Infection to Neurological Disorders
Fecal microbiota transplantation (FMT), originally endorsed for treating recurrent C. difficile infections, is rapidly diversifying into research on allergies, neurodegenerative diseases,...
Biopharma CEO Compensation and Industry M&A Trends Spotlighted
Recent analyses highlight the top-earning executives in biopharmaceuticals alongside major merger and acquisition activity, such as Merck's $10 billion acquisition of Verona Pharma. This sectoral...
FDA’s Partial Transparency on Drug Rejection Letters
The FDA has released over 200 complete response letters as part of its initiative to increase agency transparency and modernize regulatory communication. However, this release includes limitations...
Expansion of Women’s Health into Longevity Services
Tia Health, a company focused on women’s health, has launched a new longevity service line starting with a heart health emphasis. This service integrates laboratory tests and personalized provider...
Alzheimer’s Research Finds Extensive Protein Misfolding Beyond Amyloids
Johns Hopkins University researchers used advanced structural proteomic technology (LiP-MS) to identify over 200 misfolded proteins potentially contributing to age-related cognitive decline in a...
Repligen and Univercells Integrate Real-Time Virus Vector Monitoring
Repligen and Univercells Technologies have partnered to embed the MAVEN real-time glucose control platform in Univercells’ scale-X bioreactors. This innovation enables continuous measurement of...
Fecal Microbiota Transplantation’s Expanding Therapeutic Scope
Fecal microbiota transplantation (FMT), initially successful against recurrent C. difficile infections, is attracting research attention for treating diverse conditions including alopecia,...
Karyopharm Cuts Workforce Amid Strategic Challenges
Karyopharm Therapeutics announced a 20% workforce reduction, citing limited success in securing strategic alternatives to sustain operations. The company faces financial strain with a $1.6 billion...
Biotech Sector Leadership and Pay Trends
Recent analyses highlight compensation trends among top biopharma CEOs, reflecting growing investor focus on executive pay within the industry. These data provide insight into leadership...
Venture Funding Flows into Radiopharmaceutical Startups
Radiopharma developers Actithera and Nuclidium secured new venture capital rounds, underscoring investor interest in targeted radioligand therapies. Additional financing activities include private...
Behavioral Health Access Hinges on Improved Patient Navigation
Healthcare experts emphasize that better navigation systems are essential to enhance behavioral health outcomes. Emerging technologies promise improved patient support but must be complemented by...
Healthcare Supply Chains Shift Toward Strategic Resilience
Amid tariff challenges and supply uncertainties, healthcare stakeholders advocate for transforming supply chains from transactional models to strategic partnerships emphasizing domestic sourcing...
Misfolded Proteins and Alzheimer’s Expansion
Johns Hopkins University researchers have uncovered over 200 types of misfolded proteins potentially linked to age-related cognitive decline, expanding Alzheimer's disease research beyond the...