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Innovations in RNA technology and therapeutic development
Orbital Therapeutics’ next-generation circular RNA technology advances in vivo CAR-T cell therapy development, potentially offering improved delivery and gene expression profiles. Concurrently,...
Thermo Fisher Posts Q2 Beat, Sets Leadership Transition
Thermo Fisher Scientific reported a 3% year-over-year revenue increase to $10.86 billion in Q2, surpassing analyst estimates with a 6% rise in life sciences solutions revenue. Net income reached...
Sarepta's Duchenne Gene Therapy Hits Regulatory Roadblocks
Sarepta Therapeutics faced significant setbacks as the FDA demanded a halt of its Duchenne muscular dystrophy gene therapy Elevidys amid safety concerns following multiple patient deaths due to...
Sanofi Expands Respiratory Vaccine Pipeline with Vicebio Acquisition
Sanofi announced a $1.15 billion upfront acquisition of London-based biotech Vicebio, gaining an early-stage vaccine candidate targeting RSV and human metapneumovirus. The deal includes potential...
Dispatch Bio Launches with $216M to Target Solid Tumors via Novel CAR-T
Dispatch Bio debuted with $216 million in funding to develop a universal immunotherapy for solid tumors. The approach uses a dual mechanism with a viral vector tagging cancer cells and CAR-T or...
Abivax’s Ulcerative Colitis Drug Posts Dual Phase 3 Successes
French biotech Abivax reported positive results from two Phase 3 trials of its oral treatment obefazimod for moderate to severe ulcerative colitis. The pooled clinical remission rate was 16.4%...
AstraZeneca Commits $50B to U.S. Manufacturing and R&D Expansion
AstraZeneca announced plans to invest $50 billion in the U.S. over the next five years for manufacturing and research facilities, including the company’s largest-ever plant in Virginia. The...
Gene Editing Brings Hope for Rare Neurodevelopmental Disorder Treatment
Researchers utilized prime editing technology to correct five mutations responsible for alternating hemiplegia of childhood (AHC), a rare neurodevelopmental disorder. The approach demonstrated up...
Danaher Posts Revenue Growth Despite China Headwinds
Danaher’s Q2 revenue rose nearly 4% year-over-year to $5.94 billion, beating estimates driven by robust bioprocessing sales. Despite ongoing headwinds from China’s volume-based procurement and...
New Insights into Brain Aging Acceleration During COVID-19 Pandemic
A study analyzing brain scans from nearly 1,000 individuals revealed accelerated brain aging in healthy people during the COVID-19 pandemic, regardless of infection status. The effect was most...
Advances in Molecular Diagnostic Automation from Genetic Signatures Partnership
Australian molecular diagnostics firm Genetic Signatures formed a partnership with Tecan and Repado to integrate infectious disease testing with automated liquid handling and regulatory compliant...
Sanofi Expands Respiratory Vaccine Pipeline With $1.15B Vicebio Buyout
Sanofi has agreed to acquire UK-based biotech Vicebio in a deal totaling up to $1.6 billion, including $1.15 billion upfront. Vicebio’s lead asset, VXB-241, a bivalent vaccine targeting...
Sarepta Therapeutics Faces Regulatory and Safety Challenges Over Duchenne Gene Therapy
Sarepta Therapeutics has temporarily halted shipments of its Duchenne muscular dystrophy gene therapy, Elevidys, following safety concerns that include three patient deaths tied to acute liver...
FDA Rejects Replimune’s Oncolytic Virus Therapy for Advanced Melanoma
The FDA issued a complete response letter rejecting Replimune’s application for RP1, an oncolytic virus therapy designed to treat advanced melanoma. The agency cited inadequacies in trial design,...
AstraZeneca Commits $50B to U.S. Manufacturing and R&D Expansion
AstraZeneca announced a $50 billion investment plan to enhance its manufacturing and research operations in the United States through 2030. The expansion includes building the company’s...
Early Clinical Progress in Extracellular Vesicle-Based Drug Delivery in Asia-Pacific
Asia-Pacific startups like Shiftbio are leveraging extracellular vesicle (EV) technology for next-generation drug delivery systems. Shiftbio’s AI-powered nanoparticle design and manufacturing...
Alzheimer’s Disease Research Identifies Potential Combination Therapy Using Repurposed Cancer Drugs
Researchers at UCSF and Gladstone Institutes have identified a combination of FDA-approved anticancer drugs, letrozole and irinotecan, that reversed Alzheimer’s-related brain degeneration and...
New Prime Editing Approach Corrects Genetic Mutations in Rare Childhood Brain Disorder
A collaborative team led by the Broad Institute successfully employed prime editing to correct five distinct mutations responsible for alternating hemiplegia of childhood (AHC) in mouse models....
Genetic Discoveries Shed Light on Human Brain Evolution and Function
Using the recently completed telomere-to-telomere human genome reference, researchers identified approximately 250 human-specific gene duplications expressed in the brain. By creating CRISPR...
New Study Reveals Fungus Enhances Bread Wheat Micronutrient Content
Researchers from the University of Adelaide demonstrated that inoculating bread wheat with the arbuscular mycorrhizal fungus Rhizophagus irregularis increases grain size and raises levels of...