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Novartis Reignites Parkinson’s Push with $200M Arrowhead RNAi Deal
Novartis has inked a $200 million upfront licensing agreement with Arrowhead Pharmaceuticals to develop ARO-SNCA, an RNA interference therapy targeting alpha-synuclein for Parkinson’s disease and...
Ionis Pharmaceuticals Advances Triglyceride Drug with Phase 3 Wins
Ionis Pharmaceuticals announced positive Phase 3 data for olezarsen, its antisense drug targeting severe hypertriglyceridemia (sHTG). The pivotal CORE and CORE2 trials showed up to 72%...
Amgen Commits Over $600M to New US R&D Center
Amgen announced plans to invest more than $600 million to build a cutting-edge science and innovation center at its global headquarters in Thousand Oaks, California. The facility aims to...
Treeline Biosciences Surfaces with $200M Funding and Clinical Candidates
Treeline Biosciences, a stealth oncology biotech founded by veterans Josh Bilenker and Jeff Engelman, publicly disclosed its first clinical programs and a $200 million series A extension, bringing...
Mercy BioAnalytics Raises $59M to Advance Cancer Early Detection
Mercy BioAnalytics announced the close of a $59 million Series B round to support commercialization of its blood-based ovarian cancer tests designed for population screening and mass evaluation of...
FDA and NIH Launch Initiatives to Accelerate Rare Disease Gene Therapies
The FDA’s Center for Drug Evaluation and Research (CDER) and Center for Biologics Evaluation and Research (CBER) have jointly proposed a new submission program aimed at simplifying the approval...
Novartis Deepens RNA Drug Portfolio through Deals with Chinese Biotech Argo
Novartis expanded its RNA medicine collaborations with Shanghai-based Argo Biopharma, licensing discovery-stage cardiovascular RNA therapeutics with $160 million upfront and potential for billions...
AI Designs Next-Gen Antibiotics to Combat Drug Resistance
Researchers at the University of Pennsylvania have developed AMP-Diffusion, an AI-driven generative model that creates tens of thousands of novel antimicrobial peptides to combat drug-resistant...
SMART Alliance Unveils Automated RNA Modification Tool for Cancer Research
Scientists from the Singapore-MIT Alliance for Research and Technology (SMART) have developed the first automated high-throughput platform to analyze transfer RNA (tRNA) chemical modifications...
Novartis-Arrowhead Parkinson’s RNAi Deal – $200M Upfront
Novartis has licensed a preclinical RNA interference (RNAi) therapy from Arrowhead Pharmaceuticals targeting alpha-synuclein, a protein implicated in Parkinson's disease and other...
Ionis’ Olezarsen Phase 3 Triumph – Severe Hypertriglyceridemia Benefits
Ionis Pharmaceuticals reported positive Phase 3 results for olezarsen in patients with severe hypertriglyceridemia (sHTG). The antisense oligonucleotide significantly reduced fasting triglycerides...
Amgen Commits $600M to New R&D Center in California
Amgen announced a $600 million investment to establish a state-of-the-art research and development center at its Thousand Oaks headquarters. The facility will foster interdisciplinary...
Eli Lilly’s Orforglipron Hits Phase 3 Weight Loss and Diabetes Targets
Eli Lilly announced that orforglipron, a once-daily oral GLP-1 receptor agonist, met primary and key secondary endpoints in the Phase 3 ATTAIN-2 trial involving adults with obesity or overweight...
Monod Bio Secures $1.5M Gates Grant for Urine TB Diagnostic
University of Washington spinout Monod Bio was awarded a $1.5 million grant from the Gates Foundation to develop a rapid urinary diagnostic test for tuberculosis suitable for low-resource...
Crunch Protein Redirects Phagocytosis to Eliminate Harmful Cells
Researchers at Kyoto University’s iCeMS introduced a synthetic protein therapeutic named Crunch that reprograms the body's natural cell clearance process to target and engulf living harmful cells,...
Mercy BioAnalytics Closes $59M Series B for Early Cancer Detection
Mercy BioAnalytics raised $59 million in Series B funding led by Novalis and Sozo Ventures to advance commercialization of its extracellular vesicle-based blood tests for early ovarian and lung...
AI Model Predicts Anticoagulation Needs in Atrial Fibrillation
Researchers at Mount Sinai developed a graph neural network-based artificial intelligence model to better determine which atrial fibrillation patients require blood thinners to prevent stroke. By...
Biochar’s Role in Agriculture and Climate Change Mitigation
Recent studies have examined biochar's potential as a negative emission technology to improve soil health and crop yields while reducing greenhouse gas emissions. Research published in 'Discover...
Editas Medicine Advances Gene Editing for High Cholesterol
Editas Medicine revealed EDIT-401 as its lead in vivo development candidate, an innovative gene editing therapy designed to reduce LDL cholesterol by increasing LDL receptor expression through...
ViCentra Raises $85M to Scale Insulin Patch Pump and US Market Entry
ViCentra secured $85 million in Series D funding led by Innovation Industries to accelerate manufacturing expansion and launch of its next-generation Kaleido 2 patch pump for insulin delivery. The...