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Breakthroughs in Microbiome and Infectious Disease Research
Significant progress has been made in understanding the microbiome's role in disease and immunity. Studies document changes in the cervicovaginal microbiome in women living with HIV undergoing...
AI and Imaging Innovations in Healthcare
The integration of artificial intelligence and novel imaging techniques advances diagnostic and therapeutic capabilities. A generalist foundation model synergistically analyzes 2D and 3D radiology...
Boba-Like Microbeads Trap Gut Fat to Curb Weight Gain
Researchers at Sichuan University have engineered edible microbeads inspired by boba pearls that absorb dietary fats locally within the gut, offering a potential alternative to systemic weight...
AI Platform Raises $8.6M to Reduce Hospital Readmissions
Cascala Health, a Boston-based startup, secured $8.6 million in seed funding to expand its artificial intelligence platform designed for risk-bearing healthcare providers. The platform aims to...
CRISPR Screen Identifies SUV39H2's Role in Oral Cancer Virus Resistance
A genome-wide CRISPR/Cas9 screen revealed SUV39H2, a histone methyltransferase, as a key mediator of resistance to oncolytic herpes simplex virus 1 (oHSV-1) in oral squamous cell carcinoma (OSCC)....
Novel Brain-Shuttled Antibody Targets Parkinson’s Alpha-Synuclein
Researchers have developed a pioneering antibody capable of crossing the blood-brain barrier to target alpha-synuclein aggregates, the pathological hallmark of synucleinopathies such as...
Liquid Biopsy Assay Enables Sensitive Tracking of Pediatric CNS Tumors
A new personalized liquid biopsy assay named MRD4U offers unprecedented sensitivity for monitoring central nervous system tumors in children. Detailed in BMC Cancer, this genomic tool allows...
Deep Learning with MRI Predicts Prostate Cancer Spread Patterns
A novel approach integrating deep learning and multiparametric MRI-based habitat analysis accurately predicts perineural invasion in prostate cancer patients. This two-center study demonstrates...
New Biomarker and Thresholds Improve Early Diabetes Detection
A recent study using data from the National Health and Nutrition Examination Survey (NHANES) identified the Unrecognized Hyperglycemia Risk (UHR) threshold as a promising new biomarker for early...
FDA Approves First Therapy for Rare Respiratory Tumor Amid Financial Concerns
Precigen’s Papzimeos, the first FDA-approved immunotherapy for recurrent respiratory papillomatosis, has blockbuster potential in the rare tumor market. However, recent financial disclosures...
Gut Microbial Exosomes Facilitate Parkinson’s Disease Neuroprotection
New research highlights that neural stem cell-derived exosomes can alleviate neurodegeneration in Parkinson’s disease models induced by MPTP neurotoxins. These extracellular vesicles mediate...
Boba Pearl-Inspired Fat-Absorbing Microbeads Offer Novel Obesity Solution
Sichuan University scientists developed edible microbeads that selectively trap dietary fats in the gastrointestinal tract, showing promise in weight management without systemic drug exposure....
AI Startup Raises $8.6 Million to Cut Hospital Readmissions
Boston-based startup Cascala Health secured $8.6 million in seed funding to expand its artificial intelligence platform aimed at improving patient care transitions. The platform targets...
New Antipsychotic in Phase III and LB Pharma IPO Plans
LB Pharma is preparing to test the IPO market as its antipsychotic drug nears Phase III clinical trials. This development comes amid growing interest in neuropsychiatric therapeutics, with LB...
CRISPR Screen Identifies Cause of Resistance in Oral Cancer
Researchers used a CRISPR/Cas9 genome-wide screen to identify SUV39H2, a histone methyltransferase, as a key driver of resistance to oncolytic herpes simplex virus 1 (oHSV-1) therapy in oral...
Novel Brain-Shuttled Antibody Targets Parkinson’s Alpha-Synuclein
A newly engineered brain-delivered antibody targeting alpha-synuclein aggregates, implicated in synucleinopathies like Parkinson’s disease, demonstrates potential for mitigating neurodegeneration....
Generalist Radiology AI Model Integrates 2D and 3D Imaging
Researchers led by Wu, Zhang, and Zhang have developed a generalist foundational AI model that integrates both two-dimensional and three-dimensional medical imaging data at scale. This novel model...
Personalized Liquid Biopsy Advances Pediatric CNS Tumor Monitoring
The MRD4U assay represents a new personalized liquid biopsy technique designed to monitor central nervous system tumors in children with high sensitivity. This development may enable earlier...
New Biomarker Signals Early Diabetes Risk Detection
Yu and colleagues identified a novel biomarker termed Unrecognized Hyperglycemia Risk (UHR) that improves early diabetes detection. This biomarker, emerging from National Health and Nutrition...
Virtual Reality Enhances Nursing Education Through Collaboration
In a cutting-edge educational initiative, Li, Wu, and Zhang introduced virtual reality (VR) with a flipped classroom and collaborative role-playing to nursing training. This innovative approach...