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Genomic Insights into Disease and Population: Dengue Mosquito and Plasma Metabolome Studies
Two pivotal studies deliver novel genomic insights impacting public health and precision medicine. First, sequencing of over 1,200 Aedes aegypti mosquitoes reveals adaptations underlying...
UCSF Deploys CRISPR Activation to Treat SCN2A-Related Neurodevelopmental Disorders
Researchers at UCSF demonstrated that CRISPR activation of the functional SCN2A gene copy in mouse models restores synaptic maturation and mitigates seizure susceptibility, representing a...
Roche to Acquire 89bio for $3.5 Billion, Targeting NASH Market Expansion
Roche announced a definitive agreement to acquire biotech firm 89bio for up to $3.5 billion, acquiring pegozafermin, a promising FGF21 analogue in Phase III trials for moderate to severe metabolic...
AI and Automation Transform Cell Therapy Quality Control at Cellares
Cellares has launched the Cell Q platform, an automated quality control solution tailored for commercial-scale cell therapy manufacturing. Developed through strategic partnerships with Tecan,...
Endpoints 11 Recognizes Top Biotech Startups Driving Innovation in 2025
The 2025 Endpoints 11 list spotlights eleven private biotech companies demonstrating cutting-edge innovation across diverse therapeutic areas, including AI-driven drug design, in vivo CAR-T...
CDC Advisory Panel Revises COVID-19 Vaccination Recommendations Amid Controversy
The CDC’s Advisory Committee on Immunization Practices (ACIP), restructured by Health and Human Services Secretary Robert F. Kennedy Jr., postponed votes on hepatitis B birth dose and voted to...
Emerging Cancer Therapies: ADCs Advance in Precision Oncology
Antibody-drug conjugates (ADCs) continue to gain traction as a precision oncology modality, delivering cytotoxic agents directly to cancer cells and reducing systemic toxicities. Recent clinical...
FDA Approves Stealth’s First Mitochondria-Targeted Barth Syndrome Therapy
The FDA has granted approval to Stealth’s Barth syndrome therapy, marking the first mitochondria-targeted treatment option for this rare genetic disorder. Barth syndrome primarily affects cardiac...
Merck Secures FDA Approval for Subcutaneous Keytruda to Sustain Market Edge
Merck received FDA clearance for a new subcutaneous formulation of Keytruda, its blockbuster cancer immunotherapy. This novel delivery method aims to improve patient convenience and maintain...
Dualitas Raises $65 Million to Advance Bispecific Drugs for Autoimmune Diseases
San Francisco-based Dualitas Therapeutics has secured $65 million in a Series A funding round to develop bispecific antibodies that engage two targets on the same immune cell, enhancing...
Genomic Insights Link Oral Microbiome to Elevated Pancreatic Cancer Risk
A landmark prospective study analyzing oral microbiomes of over 122,000 participants identified 27 bacterial and fungal species associated with a 3.5-fold increased risk of pancreatic cancer. The...
Roche Acquires 89bio for $2.4 Billion, Expanding in Liver Disease Therapeutics
Roche announced a definitive agreement to acquire 89bio, securing pegozafermin, a late-stage FGF21 analogue in Phase III trials for moderate to severe metabolic dysfunction-associated...
Endpoints 11 Spotlights Biotech Innovators Driving Next-Gen Therapeutics
The prestigious Endpoints 11 recognizes eleven private biotech companies distinguished by rapid innovation across diverse modalities including AI-driven drug discovery, in vivo CAR-T therapies,...
CDC Vaccine Panel Alters COVID-19 and Childhood Vaccine Recommendations
The CDC’s Advisory Committee on Immunization Practices (ACIP), recently reshaped by Appointee RFK Jr., postponed a vote on delaying the newborn hepatitis B vaccine and voted to remove the...
AI Advances in Healthcare Enable Multi-Disease Prediction and Drug Discovery
Innovations in artificial intelligence are transforming healthcare with tools like Delphi-2M, an AI model predicting over 1,000 disease risks decades ahead using patient health records and...
Latest Regulatory Movements: FDA Rescinds LDT Rule, New Device Clearances
The FDA has officially rescinded the rule expanding its authority over laboratory-developed tests following a federal court decision, reverting oversight to prior regulations. Meanwhile, novel...
FDA Approves Subcutaneous Keytruda to Extend Blockbuster's Market Life
The US Food and Drug Administration granted approval for a new subcutaneous formulation of Merck's Keytruda cancer therapy, aiming to prolong the commercial competitiveness of the world's leading...
Roche Acquires 89bio for $3.5 Billion to Boost Metabolic Liver Disease Portfolio
Roche AG announced a $3.5 billion deal to acquire 89bio Inc., securing the rights to pegozafermin, a late-stage FGF21 analogue in Phase III development targeting metabolic dysfunction-associated...
Dualitas Therapeutics Raises $65 Million for Bispecific Immunology Drug Development
Bay Area startup Dualitas Therapeutics secured $65 million in Series A funding to advance its bispecific antibody platform designed to target two receptors on the same immune cell, aiming to...
CDC Vaccine Panel Postpones Vote on Delaying Newborn Hepatitis B Vaccine
The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices deferred voting on a proposal to delay the first hepatitis B vaccine dose for infants born to mothers...