The U.S. CDC’s Advisory Committee on Immunization Practices (ACIP) underwent a controversial reconstitution after Health and Human Services Secretary Robert F. Kennedy Jr. dismissed all prior vaccine-expert members and appointed new individuals, some with nontraditional views on vaccines. The new panel signaled plans to re-evaluate the full childhood immunization schedule, provoking concern among public health experts and pediatricians about potential impacts on vaccine confidence. Recent ACIP meetings included votes to remove thimerosal from flu vaccines due to safety debates and endorsed new monoclonal antibody prophylaxis for infant RSV. The shakeup has led to public and professional calls for evidence-based immunization policies.