Nature Biotechnology published preclinical studies showing focused ultrasound cleared intracranial debris in mouse models of hemorrhagic stroke, reduced inflammation, and improved functional recovery. The technique accelerated microglial and phagocytic clearance of necrotic material and decreased secondary damage in treated animals. Authors proposed that removing debris mitigates prolonged neuroinflammation and improves repair trajectories; the work provides a mechanistic rationale for translating ultrasound debris‑clearance into human trials. While promising, the studies are preclinical and will require safety and device‑parameter optimization before clinical testing in hemorrhagic stroke patients.