Broad Clinical Labs, with Roche’s early‑access SBX platform, reported end‑to‑end sequencing and analysis of human genomes in under four hours, setting a new clinical speed benchmark and spotlighting potential same‑day diagnostics for critically ill infants. Separately, Sophia Genetics launched a Digital Twins module to simulate disease trajectories using multimodal clinical, genomic and imaging data for oncology research. Together these advances underscore a push to compress diagnostic timelines and use computational patient replicas to prioritize therapies and clinical trial matches — though both groups note further validation and regulatory pathways are required for routine clinical deployment.