UC San Diego received up to $25,771,771 from ARPA‑H to develop a patient‑specific, fully functional 3D‑bioprinted liver under the PRINT program. The multidisciplinary effort, led by Shaochen Chen and collaborators, aims to create made‑to‑order livers grown from a patient’s own cells to remove the need for donor organs and lifelong immunosuppression. The award covers a 60‑month project timeline focused on scale-up and vascularization. Chen’s team says they will integrate AI tools to design complex vascular networks and optimize rapid, high‑resolution bioprinting. Success would alter transplant paradigms and reduce organ shortage pressures, while raising questions about manufacturing scale, regulatory pathways for engineered organs, and long‑term functional validation in preclinical and clinical settings.