One Biosciences will establish its first U.S. location in Albany, New York, building and staffing a high-complexity lab and computational analytics operation. Institut Curie-backed, the company plans to use AI-driven single-cell technologies to characterize tumor ecosystems for pharma, biotech, and academic collaborators. Empire State Development will support the expansion through up to $525,000 in performance-based Excelsior Jobs Program tax credits tied to job commitments. One Biosciences expects to invest $18 million and create 42 life science jobs over the next five years. Industry impact: the move adds capacity to U.S. single-cell profiling infrastructure at a time when sponsors seek deeper tumor microenvironment readouts for clinical stratification and companion diagnostics development.