Two transcriptome‑wide association studies (TWAS) reported independently uncover new genes causally linked to diabetic nephropathy. Teams used integrated genetic and expression datasets to prioritize candidates and nominate pathways involved in glomerular injury and fibrosis. One paper (Genome Medicine) and a corroborating TWAS provide convergent findings that refine gene-level targets for functional follow-up and drug discovery. The studies recommend in vitro and in vivo validation to translate genetic associations into therapeutic hypotheses.