A laboratory study found that accumulation of trehalose‑6‑phosphate (T6P) in Candida auris alters its susceptibility to echinocandin antifungals. The research team demonstrated biochemical and phenotypic shifts that reduced resistance in cell models, suggesting a metabolic lever to resensitize drug‑resistant strains. Given rising global C. auris outbreaks and limited antifungal classes, the findings offer a potential adjunct strategy for overcoming echinocandin resistance. Drug developers and clinical microbiology labs may pursue small molecules or adjuvants that modulate T6P pathways alongside existing antifungal regimens.