A research team led by Pia Cosma at the Centre for Genomic Regulation (Barcelona Institute of Science and Technology) developed the Eye-in-a-Care-Box (ECaBox), a perfusion device intended to preserve freshly removed eyes for transplantation. The device supplies oxygen-rich fluid through the ocular artery and allows imaging while the eye is maintained outside the body. In pig eye experiments, eyes kept at room temperature degraded quickly, even when cooled to 4°C, but perfused eyes showed significantly higher viability after 24 hours. The perfused eyes also appeared able to respond to light, suggesting potential functionality post-transplant. If translated, ECaBox could extend the usable time window for donor eye tissue and address a key limitation of current eye preservation workflows—rapid degeneration after excision.