Thermo Fisher Scientific filed notice of a facility closure at 27 Forge Parkway in Franklin, Massachusetts, and plans layoffs affecting more than 100 employees, according to reporting on the company’s announcement. The Waltham‑based instrument and reagent giant did not tie the move to a specific product line in the public notice but framed it as part of operational consolidation. Site closures at major suppliers can ripple through academic and commercial labs that depend on local manufacturing and service networks. For CROs, instrument customers, and regional biomanufacturing hubs, the shutdown could mean longer lead times, reallocated service resources, and local workforce displacement.