A novel study led by researchers at the University of California San Diego’s Sanford Stem Cell Institute reveals that human hematopoietic stem and progenitor cells (HSPCs) experience accelerated aging when exposed to spaceflight conditions aboard the International Space Station. Utilizing AI-driven nanobioreactor systems for real-time analysis, the team observed increased DNA damage, reduced regenerative capacity, and shortened telomere length in cells after about one month of space exposure. These findings have profound implications for astronaut health on long-duration missions and also provide valuable insights into terrestrial aging and age-related diseases such as cancer.