Researchers reported that a 564-gene nanopore adaptive sampling panel can detect Parkinson’s disease variants, structural rearrangements, and repeat expansions in a single run, correctly identifying 85% of known pathogenic variants. The workflow aims to compress multiple test types into one sequence, potentially accelerating genetic evaluation. If further validated in broader cohorts, the approach could reduce turnaround times and improve accessibility for patients needing comprehensive genetic workups beyond single-variant assays.