Researchers reported a scalable method to produce thousands of uniform human kidney organoids and demonstrated their delivery and short‑term integration into perfused porcine kidneys during ex vivo machine perfusion. The technique, published in Nature Biomedical Engineering and led by groups at IBEC and collaborating institutions, combines human pluripotent stem cell‑derived organoids with normothermic perfusion of pig kidneys to monitor viability and engraftment in real time. The teams showed reproducible organoid differentiation into multiple renal cell types and described protocols to infuse organoids into porcine vasculature during organ preservation. A separate announcement documented the first porcine transplants using porcine kidneys modified with human renal organoids in pigs, signaling progress from production toward functional testing in a large‑animal context. The advance addresses two persistent barriers in regenerative nephrology—scalability of organoid manufacture and a translational testing platform—and lays groundwork for organoid‑enabled cell therapies, ex vivo gene modification, and preclinical drug screens.