Two teams published new RNA-editing platforms that expand the scope and precision of transcript rewriting. One Nature Biotechnology paper describes a single-strand deaminase-assisted system that can simultaneously rewrite multiple bases within a single RNA transcript. A related report introduced AIM (Adjustable RNA Information Manipulation), a controllable platform for site-specific RNA edits. RNA editing operates on transient transcripts rather than genomic DNA, offering a therapeutic route with reduced permanent genotoxic risk.
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