A team published a single‑strand deaminase‑assisted platform that enables multi‑base editing within individual RNA transcripts. The study, reported in Nature Biotechnology, demonstrates a controllable approach to rewrite multiple adenosines in a single RNA molecule, expanding the toolkit for transient transcript modulation. Researchers led the work to deliver precise, programmable RNA edits without altering DNA. The platform could accelerate functional studies and short‑lived therapeutic interventions where durable DNA changes are undesirable. For readers: single‑strand deaminases chemically convert specific RNA bases (e.g., A→I) to change codons or regulatory motifs without genomic modification.