Regulatory landscapes and leadership dynamics continue to evolve. The U.S. federal court ruled mass layoffs at the Department of Health and Human Services likely unlawful, suspending implementation amid lawsuits citing constitutional overreach. The U.K. MHRA issued new guidance clarifying digital mental health technology classifications under software medical device regulations. Industry sees notable leadership changes with executive retirements and appointments at Roche, Mammogen, Max Planck Institute, and Gradientech. Policy discussions around vaccine recommendations and scrutiny intensify as CDC expands RSV vaccination guidance and legislative inquiries target Pfizer’s COVID-19 vaccine development transparency.