Hydrogen sulfide is shown to enhance wheat resistance to stripe rust by activating the autophagy pathway. Researchers report that H2S increases TaATG6c persulfidation, effectively turning on cellular recycling mechanisms that restrict the fungal pathogen. The work matters for translation of gas-molecule biology into crop protection strategies, because it links a small reactive sulfur species to a specific autophagy regulator rather than treating stress resistance as a generic outcome. While the study is in plants, the TFEB/autophagy axis it highlights aligns with growing interest in “master recycling” control across cancer and lysosomal disorders.