Researchers at the Coriell Institute created a publicly available iPSC resource backed by HiFi long-read whole-genome sequencing, pharmacogenomic and HLA annotations, and web-based tools for variant search. The resource is designed to support lab modeling by improving variant resolution compared with short-read approaches. The long-read component is intended to reduce missingness in complex regions and structural variants, which can matter when iPSCs are used for disease modeling, drug response studies, and immune-relevant experiments. The addition of pharmacogenomic and HLA data broadens the utility for translational research and immunology-linked modeling. For platform builders and academic groups, the dataset’s combination of deep sequencing plus search tooling lowers the barrier to selecting appropriate iPSC lines and interpreting genetic backgrounds across studies.