Researchers reported a strategy that accelerates endothelialization of 3D‑printed vascular grafts by leveraging interactions between circulating endothelial progenitor cells (EPCs) and the perivascular niche. The team demonstrated faster vessel healing and improved graft integration in preclinical models, citing specific molecular mediators of EPC recruitment and differentiation. The work advances tissue‑engineered vascular grafts toward clinical utility by improving early patency and biocompatibility. For readers: endothelialization is the process by which an inner vessel lining is formed, critical to graft function and thrombosis prevention.