A new smart contact lens approach pairs continuous intraocular pressure (IOP) monitoring with closed-loop, adaptive drug delivery for glaucoma. In Science Translational Medicine, Terasaki Institute for Biomedical Innovation researchers led by Principal Investigator Dr. Yangzhi Zhu described an all-polymer smart contact lens that continuously measures IOP in real time and triggers responsive drug delivery when pressure exceeds a defined threshold. The platform targets the gap between intermittent clinic readings and the need for frequent, personalized IOP control. The work also complements a broader device pipeline around adaptive ocular therapeutics, with potential implications for reducing progression risk through earlier intervention based on actual IOP dynamics.